Guardians vs Nationals MLB Odds, Picks, and Predictions (May 25)

Published May 25, 9:58am ET by

Demilade Adelekun - Betting Preview Analyst and Sports Writer

Last updated May 25, 9:58am ET

Pick status
baseball

Updated May 25, 9:58am ET

  • The Cleveland Guardians open a road series against the Washington Nationals on Monday at Nationals Park.
  • Tanner Bibee takes the mound for Cleveland.
  • Zack Littell gets the start for Washington.
Washington Nationals vs. Cleveland Guardians Overview Watch On: MLB TV

DATE & TIME

Monday, May 25 Β· 1:05 PM ET
Washington Nationals
Nationals Park
Washington, D.C.
Cleveland Guardians
GAME ODDS
BetOnline
Washington Nationals +148
Cleveland Guardians -180

Bibee Has Been Consistent and His Numbers Back It Up

Tanner Bibee is 3.75 ERA and 4.03 FIP. Those are numbers that sit close enough together to say he has been pitching to his results. He is not running above or below what his process deserves. Bibee works efficiently, limits the kind of extended damage sequences that inflate ERAs quickly, and has been a reliable arm for a Guardians team that has won eight of its last ten games. He will give Cleveland innings tonight.

Jose Ramirez continues to be the engine of the Cleveland offense, and the Guardians have been scoring runs at a rate that makes their road performances dangerous. Eight wins in the last ten covers a lot of park effects.

Littell's ERA Is the Story

Zack Littell has a 5.83 ERA and a 7.40 FIP. The ERA is bad. The FIP being 1.57 runs worse means the 5.83 is the version where things broke his way. He has been allowing the kind of contact that should produce more damage than the box scores have captured, which means the ERA has been running at a discount on the actual performance. CJ Abrams and James Wood give Washington a legitimate top of the order, and the Nationals are 6-4 in their last ten. The lineup can score. Littell just has to last long enough for them to do it.

Guardians vs Nationals Pick

-180 is a real number to lay. What makes it worth it: Littell's FIP is 7.40 in a season where his ERA is already 5.83, meaning the results the market is seeing are the good version of his 2026. Bibee is pitching to a 4.03 FIP, and Cleveland is 8-2 in their last ten. The edge here is genuine, and the juice reflects a real gap rather than manufactured confidence. Guardians on the road.

Pick: Cleveland Guardians -180

Pick
Cleveland Guardians -180
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