Last updated Sep 11, 5:04am ET

A clash between two likely competitors in the playoffs is set for the MLS this weekend. The hosts will be aiming to secure their spot in the post-season, but will they rank among the most likely Vancouver vs. Philadelphia picks?

The Whitecaps have enjoyed a memorable 2025 season, winning 14 of their 27 matches and suffering just six defeats. They come into this round having avoided defeat in each of their last three competitive matches.

Philadelphia have already secured their spot in the post-season, and they currently sit top of the Eastern Conference standings after winning 17 of their 29 matches.

Vancouver vs. Philadelphia Overview

StatInformation
Date & TimeSaturday, September 13, 2025 @ 9:30 PM ET
WhereBC Place, Vancouver, Canada
How to WatchApple TV

Odds

Match ResultOdds
Vancouver+115
Draw+250
Philadelphia+235

Vancouver vs. Philadelphia Head-to-Head Record

TotalVancouverPhiladelhiaDraws
Wins10334
MLS Games10334
Goals231112 

Philadelphia have avoided defeat in their last three matches against the Whitecaps. However, this will be a first clash between the sides since a 1-1 draw in April 2019.

Vancouver Team News

The Whitecaps will likely keep faith with the same starting eleven that starred in the recent 3-2 win against St. Louis. Thomas Muller will once again be deployed in the number ten role.

Possible Lineup

Takaoka (GK); Ocampo, Halbouni, Blackmon, Laborda; Berhalter, Cubas; Sabbi, Muller, Nelson; White

Philadelphia Team News

The Union could make changes to their starting eleven ahead of the U.S. Open Cup semi-final against Nashville in midweek. Olwethu Makhanya is suspended after being sent off against Cincinnati.

Possible Lineup

Rick (GK); Sullivan, Glesnes, Mbaizo, Wagner; Uhre, Jacques, Lukic, Rafanello; Damiani, Vassilev

Vancouver vs. Philadelphia Picks

This will be a big opportunity for the Whitecaps to secure their spot in the playoffs. Their chances of achieving that are enhanced based on the fact that the Union have a big cup semi-final in midweek. Therefore, a home win is among the preferred Vancouver vs. Philadelphia picks this weekend.

Pick
Vancouver Whitecaps (+115)
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Alex Dudley
Alex Dudley

Sports Analyst and Betting Expert

Alex has over 15 years of experience in sports betting, specializing in soccer and horse racing. He uses his deep knowledge of markets and strategies to guide readers through disciplined and informed betting.

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