Liga MX: San Luis vs. Club America Picks, Odds, and Preview (Sep 24)
The visiting side will be aiming to break a two-game winless run in Liga MX this week. Can they achieve...

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The visiting side will be aiming to break a two-game winless run in Liga MX this week. Can they achieve that feat on the road? You can find our San Luis vs. Club America picks here.
Club America remains in a prominent position in the league standings at this stage after winning five of their opening nine matches. However, a return to form will be required after failing to win in their previous two.
San Luis could arguably bring better form into this round after going two without a defeat. That includes a victory in the previous round of Liga MX matches.
San Luis vs. Club America Overview
Stat | Information |
---|---|
Date & Time | Wednesday, September 24, 2025 @ 11:00 PM ET |
Where | Estadio Alfonso Lastras, Mexico |
How to Watch | TUDN |
Odds
Match Result | Odds |
---|---|
San Luis | +420 |
Draw | +316 |
Club America | -162 |
San Luis vs. Club America Head-to-Head Record
Total | San Luis | Club America | Draws | |
---|---|---|---|---|
Wins | 38 | 10 | 22 | 6 |
Liga MX Games | 33 | 8 | 21 | 4 |
Goals | 107 | 40 | 67 |
Club America recorded a 3-0 success in the previous encounter between these two sides. That win was a perfect response after losing two of their last three against San Luis.
San Luis Team News
A largely unchanged line up is expected to be named by San Luis on Wednesday following an excellent 4-1 victory against Santos Laguna. Joao Pedro netted twice in the recent Liga MX win.
Possible Lineup
Rodriguez (GK); Acosta, Bambu, Aguila, Sanabria; Lamonge, Macias; Galdames, Bouquet, Alvarez; Pedro
Club America Team News
Club America are likely to keep faith with the same eleven that recently played out a deserved 2-2 draw against Monterrey.
Possible Lineup
Malagon (GK); Borja, Castillo, Caceres, Espinoza; Cervantes, Reyes; Saint-Maximum, Gutierrez, Zendejas; Zuniga
San Luis vs. Club America Picks
San Luis have enjoyed some positive recent results against Club America. But, it remains challenging to overlook the prospect of an away victory when making San Luis vs. Club America picks based on the recent results of both teams.
Pick
Club America (-162)
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