The visiting side will be aiming to break a two-game winless run in Liga MX this week. Can they achieve that feat on the road? You can find our San Luis vs. Club America picks here.

Club America remains in a prominent position in the league standings at this stage after winning five of their opening nine matches. However, a return to form will be required after failing to win in their previous two.

San Luis could arguably bring better form into this round after going two without a defeat. That includes a victory in the previous round of Liga MX matches.

San Luis vs. Club America Overview

StatInformation
Date & TimeWednesday, September 24, 2025 @ 11:00 PM ET
WhereEstadio Alfonso Lastras, Mexico
How to WatchTUDN

Odds

Match ResultOdds
San Luis+420
Draw+316
Club America-162

San Luis vs. Club America Head-to-Head Record

TotalSan LuisClub AmericaDraws
Wins3810226
Liga MX Games338214
Goals1074067 

Club America recorded a 3-0 success in the previous encounter between these two sides. That win was a perfect response after losing two of their last three against San Luis.

San Luis Team News

A largely unchanged line up is expected to be named by San Luis on Wednesday following an excellent 4-1 victory against Santos Laguna. Joao Pedro netted twice in the recent Liga MX win.

Possible Lineup

Rodriguez (GK); Acosta, Bambu, Aguila, Sanabria; Lamonge, Macias; Galdames, Bouquet, Alvarez; Pedro

Club America Team News

Club America are likely to keep faith with the same eleven that recently played out a deserved 2-2 draw against Monterrey.

Possible Lineup

Malagon (GK); Borja, Castillo, Caceres, Espinoza; Cervantes, Reyes; Saint-Maximum, Gutierrez, Zendejas; Zuniga

San Luis vs. Club America Picks

San Luis have enjoyed some positive recent results against Club America. But, it remains challenging to overlook the prospect of an away victory when making San Luis vs. Club America picks based on the recent results of both teams.

Pick
Club America (-162)
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Alex Dudley
Alex Dudley

Sports Analyst and Betting Expert

Alex has over 15 years of experience in sports betting, specializing in soccer and horse racing. He uses his deep knowledge of markets and strategies to guide readers through disciplined and informed betting.

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