MLS: San Diego vs. Minnesota Picks — Western Conference Playoff Hopes to Play Out Thriller? (Sep 13)

Two of the standout teams in the Western Conference lock horns in the MLS on September 13, as San Diego vs. Minnesota is staged. Find our picks here.

The home side currently sit top of the Western Conference standings, and have won 17 of their 29 matches this season. San Diego are also the best attacking team in the Conference in 2025, having netted 54 goals.

Minnesota will still have aspirations of finishing top of the Conference standings, but they sit five points behind their opponents.

San Diego vs. Minnesota Overview

Odds

San Diego vs. Minnesota Head-to-Head Record

This weekend’s clash will only be the second meeting between San Diego and Minnesota. The previous fixture ended in a thrilling 4-2 success for San Diego in June.

San Diego Team News

San Diego are unlikely to change a winning team, despite having already assured their spot in the Western Conference playoffs.

Possible Lineup

Dos Santos (GK); McVey, Duah, McNair, Bombino; Godoy, Tverskov, De La Torre; Dreyer, Valakari, Lozano

Minnesota Team News

Minnesota have been well drilled throughout the 2025-26 season, and there will be little reason to change their system. Tani Oluwaseyi could be recalled to the starting eleven.

Possible Lineup

Clair (GK); Markanich, Romero, Boxall, Diaz, Hlongwane; Lod, Trapp, Rosales; Pereyra, Oluwaseyi

San Diego vs. Minnesota Picks

Despite being heavy favorites this weekend, it could be worth taking on San Diego, as they have thrived on the road throughout the campaign.

Minnesota have won 50% of their away matches, and have a better defensive record on the road than they have in home fixtures. Therefore, the value could be for the visitors when making San Diego vs. Minnesota picks.