Last updated Aug 13, 4:48am ET

Liga MX action continues this weekend, as two sides that have struggled for wins so far this term collide. You can find the odds and our Puebla vs. San Luis picks here.

Puebla have been underperforming since the opening day of the season, and they come into this round after losing three of their last four matches. They have already allowed a league-high of 12 goals in 2025.

San Luis sit just two places higher than their opponents this weekend, but they are winless since the opening day of the campaign. The visitors have suffered defeats in each of their last three matches.

Puebla vs. San Luis Overview

StatInformation
Date & TimeFriday, August 15, 2025 @ 9:00 PM ET
WhereEstadio Cuauhtemoc, Mexico
How to WatchTUDN

Odds

Match ResultOdds
Puebla   
Draw 
San Luis 

Puebla vs. San Luis Head-to-Head Record

TotalPueblaSan LuisDraws
Wins2710125
Liga MX Games249114
Goals653233 

San Luis boast an excellent recent record against Puebla, winning each of the last five encounters. That includes a 2-1 away success in the previous meeting between the sides back in January.

Puebla Team News

The hosts will be without the suspended Ariel Gamarra this weekend. Wholesale changes could be made following a heavy 7-0 loss against Tigres UANL last weekend.

Possible Lineup

J. Rodriguez (GK); E. Orona, J, Rivas, N. Diaz, M. Perez, R. Castillo, F. Moyano, E. Lozano, E. Gomez, F. Ochoa, R. Marin

San Luis Team News

Joao Pedro will be suspended this weekend after being sent off in the home defeat against Cruz Azul in the previous encounter.

Possible Lineup

A. Rodriguez (GK); J. Sanabria, Juanpe, E. Aguila, J. Suarez, O. Macias, B. Galdames, R. Dourado, M. Alvarez, M. Kilmowicz, A. Cruz

Puebla vs. San Luis Picks

It has been a challenging start to the new season for both of these teams, and wins have been hard to achieve. However, the away win could be a preference when making Puebla vs. San Luis picks, based solely on their excellent head-to-head record against the hosts.

Pick
San Luis
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Alex Dudley
Alex Dudley

Sports Analyst and Betting Expert

Alex has over 15 years of experience in sports betting, specializing in soccer and horse racing. He uses his deep knowledge of markets and strategies to guide readers through disciplined and informed betting.

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