Premier League Matchday 4 Picks & Preview (Sep 13-14)
Exciting action in England’s top-flight resumes this weekend following the September international break. A stunning round of matches is set,...
0 Published Sep 12, 4:35am ET by Alex Dudley
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Last updated Sep 12, 4:35am ET
Exciting action in England’s top-flight resumes this weekend following the September international break. A stunning round of matches is set, with the weekend headlines by Man City vs. Man United on Sunday. You can find our Premier League picks for matchday four here.
Premier League Matchday 4 Schedule
| Stat | Information |
|---|---|
| When | Saturday, September 13, 2025 – Sunday, September 14, 2025 |
| Where | Various Stadiums, England |
| How to Watch | USA/NBC |
Premier League Matchday 4 Picks
Arsenal vs. Nottingham Forest
Ange Postecoglou takes charge of Nottingham Forest for the first time at the Emirates on Saturday, as Forest chase a return to form following a shock defeat against West Ham.
Their chances appear slim after winning just two of their 16 EPL fixtures against Arsenal. The Gunners looked short of quality in the defeat against Liverpool before the break, but this appears to be a much more straightforward assignment.
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Pick
Arsenal (-265)
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Everton vs. Aston Villa
Jack Grealish comes up against his boyhood club on Saturday, as Everton host Aston Villa. The Toffees are winless in their last 12 EPL fixtures against Villa, while the Midlands side have won four of their last five away matches against Everton.
However, recent form could be the angle worth following, as David Moyes has masterminded an excellent start to the season, with Everton winning five of their last six.
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Pick
Everton (+150)
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Crystal Palace vs. Sunderland
Sunderland have won both of their home matches since returning to the Premier League, but they were disappointingly beaten by Burnley in their only match on the road.
Interestingly, five of the last six meetings between these sides have been won by the away team. But, Palace have gone nine without defeat, and this looks like a solid chance to get a much-needed win.
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Pick
Crystal Palace (-152)
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Bournemouth vs. Brighton
Brighton upset the odds before the international break after coming from behind to beat Man City. Meanwhile, the Seagulls hold the advantage based on previous meetings between the sides, winning five of the last six.
But, Bournemouth’s solid start to the season deserves respect, as they have made their best beginning to a new season since 2018-19. The points could be shared.
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Pick
The Draw (+255)
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Newcastle vs. Wolves
A busy Deadline Day saw Newcastle add two strikers to their squad, and both could feature against a defensively weak Wolves this weekend.
Despite going five EPL matches without a win, Newcastle have lost just two of their 20 matches against Wolves. Meanwhile, the visitors have registered just a single win in 22 top-flight visits to St. James’ Park. Home banker.
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Pick
Newcastle (-225)
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Fulham vs. Leeds
Fulham have made a patchy start to the new season, and have failed to win in their last four EPL fixtures across the last two seasons.
But, the Cottagers have suffered just one defeat in their last five home fixtures against Leeds in the Premier League. Fulham’s performances have been better than their points tally suggests, and a first win could be achieved on Saturday.
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Pick
Fulham (-102)
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West Ham vs. Tottenham
A fascinating London derby is one of two late games in the Premier League. West Ham have won just one of their last seven EPL fixtures against Tottenham, while Spurs have lost ten of their last 16 London derbies.
With the pressure on the hosts, and manager Graham Potter, it could be worth following the trend of draws. Each of the last three meetings between the sides at the London Stadium have ended in ties.
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Pick
The Draw (+265)
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Brentford vs. Chelsea
Home wins have been a rarity when Brentford and Chelsea meet, with just one of the eight EPL fixtures seeing a home success. Brentford have won three times against the Blues, but all wins have come on the road. It could be hard to overlook the prospect of an away win after Chelsea have started the season in strong form with two wins from three.
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Pick
Chelsea (-130)
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Burnley vs. Liverpool
Record signing Alexander Isak could feature for Liverpool on Sunday, as the Reds travel to Turf Moor.
Burnley have suffered defeats in 14 of their last 18 EPL matches against Liverpool, which includes losses in each of the last five. Liverpool have also registered wins in eight of their last nine away matches against the Clarets. An away win looks hard to overlook when making Premier League picks.
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Pick
Liverpool (-295)
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Man City vs. Man United
The big match of the weekend comes from the Etihad, as Man City and Man United collide. Despite the negativity surrounding the Red Devils, they come into this round sitting above their city rivals.
Away wins have been a common outcome in the derby, with just six of the last 20 meetings between the sides ending in a home win. United’s resurgence could continue with a famous success at the Etihad.
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Pick
Man United (+335)
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