Liga MX: Monterrey vs. Santos Laguna Picks, Odds, and Preview (Sep 27)
It has been a patchy period of form for one of the hot favorites to win the Liga MX title...

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Last updated Sep 25, 4:31am ET
It has been a patchy period of form for one of the hot favorites to win the Liga MX title this season. However, they will be aiming to get back to winning ways on Sep 27. You can find our Monterrey vs. Santos Laguna picks here.
Monterrey comes into this round sitting third in the Liga MX standings after failing to win in each of their last two. A return to form will be expected following a shock defeat in midweek.
Santos Laguna’s confidence should be high after a victory in their latest fixture in the Mexican top-flight. That success ended a four-game winless sequence in Liga MX.
Monterrey vs. Santos Laguna Overview
Stat | Information |
---|---|
Date & Time | Saturday, September 27, 2025 @ 9:00 PM ET |
Where | Estadio BBVA, Mexico |
How to Watch | TUDN |
Odds
Match Result | Odds |
---|---|
Monterrey | -320 |
Draw | +490 |
Santos Laguna | +750 |
Monterrey vs. Santos Laguna Head-to-Head Record
Total | Monterrey | Santos Laguna | Draws | |
---|---|---|---|---|
Wins | 66 | 25 | 19 | 22 |
Liga MX Games | 55 | 21 | 15 | 19 |
Goals | 187 | 105 | 82 |
Monterrey have recorded victories in each of the last five head-to-head meetings between these sides. Their latest success was a 4-2 victory in March.
Monterrey Team News
It’s likely that the hosts will make a couple of changes to their starting eleven this weekend following 6-2 defeat against Toluca in midweek. Anthony Martial could be in line for a start.
Possible Lineup
Mele (GK); Ramos, Chavez, Reyes; Aguirre, Guzman, Oliver, Arteaga; Corona, Canales; Martial
Santos Laguna Team News
Bruno Barticciotto will be suspended this weekend after being sent off in Santos Laguna’s 1-0 victory against Club Tijuana in midweek.
Possible Lineup
Lopez (GK); Abella, Sanchez, Balanta, Amione; Mariscal, Guemez; Sordo, Carrillo, Palacios; Ocejo
Monterrey vs. Santos Laguna Picks
Monterrey will be aiming to put their midweek hammering behind them quickly on Saturday. Their dominant historical record against this weekend’s opponents deserves huge respect, and we could see a comprehensive showing on their return to action. Therefore, the preference is for a home win when making Monterrey vs. Santos Laguna picks.
Pick
Monterrey (-320)
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