Last updated Jul 16, 4:12am ET

Guadalajara will be among the leading chances for Liga MX success this season, and they will be aiming to kick off their campaign with an impressive showing against Leon.

The Mexican giants will play their opening two matches to start the season, before their attention swiftly turns to the Leagues Cup, which kicks off at the start of August.

Leon will be hoping to make a more favorable impression than they did on the opening day of the season this weekend. They were disappointing at home against San Luis, eventually losing 1-0.

Leon vs. Guadalajara Overview

StatInformation
Date & TimeSaturday, July 19, 2025 @ 9:00 PM ET
WhereEstadio Leon, Leon, Mexico
How to WatchTUDN

Odds

Match ResultOdds
Leon+173
Draw+224
Guadalajara+167

Leon vs. Guadalajara Head-to-Head Record

TotalLeonGuadalajaraDraws
Wins3711179
Liga MX Games2811125
Goals793346 

There is little to separate these sides based on the recent meetings. Guadalajara have won two of the last three, which includes a 2-0 success in a friendly in June. However, Leon have recorded victories in two of the previous three competitive meetings.  

Leon Team News

Leon will have a fully fit squad available for this second home match in succession this weekend.

Possible Lineup

O. Jimenez (GK); S. Rosales, J. Barreiro, A. Frias, S. Reyes, R. Echeverria, F. Beltran, J. Ramirez, I. Moreno, C. Cisneros, E. Ayon

Guadalajara Team News

Gabriel Milito has no injury concerns ahead of this clash. Efrain Alvarez and Richard Ledezma are both in line for competitive debuts on Saturday evening.

Possible Lineup

C. Vargas (GK); R. Ledezman, G. Aguirre, H. Nervo, R. Lozano, A. Rocha, J. Marquez, D. Gonzalez, E. Aguirre, E. Alvarez, J. Hernandez

Leon vs. Guadalajara Picks

A close encounter is expected in Liga MX this weekend, and cases can be made for both teams.

However, Leon’s performance last weekend was far below the level that we have come to expect, and we fully expect them to bounce back to winning ways in their second home match of the 2025 season.

Pick
Leon (+173)
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Alex Dudley
Alex Dudley

Sports Analyst and Betting Expert

Alex has over 15 years of experience in sports betting, specializing in soccer and horse racing. He uses his deep knowledge of markets and strategies to guide readers through disciplined and informed betting.

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