Liga MX: Club America vs. Guadalajara Picks, Odds, and Preview (Sep 13)

The exciting action in Liga MX resumes this weekend, and a fascinating clash seeing Club America vs. Guadalajara will be staged. You can find our picks here.

Club America have been excellent across the opening weeks of the new season, and they are one of two teams that are yet to suffer a defeat. They come into this round having won each of their last four matches.

Contrastingly, Guadalajara have endured a miserable start to the 2025 campaign. They have won just once in their opening six matches, and they have suffered defeats in three of their last four.

Club America vs. Guadalajara Overview

Odds

Club America vs. Guadalajara Head-to-Head Record

Club America were straightforward 4-0 winners in the previous encounter between the sides in March. However, that win broke a two-game winless sequence against Guadalajara.

Club America Team News

High-flying Club America will see no reason to change a winning formula this weekend. Therefore, an unchanged eleven following a win over Pachuca could be named.

Possible Lineup

Malagon (GK); Borja, Lichnovsky, Caceres, Espinoza; Sanchez, Reyes; Zendejas, Fidalgo, Rodriguez; Aguirre

Guadalajara Team News

The visitors could make a couple of changes to the team that lost against Cruz Azul before the international break. Javier Hernandez could be handed a start.

Possible Lineup

Rangel (GK); Campillo, Sepúlveda, Tapias; Alvarado, Romo, Gutiérrez, B. González; S. González. Hernandez, Alvarez

Club America vs. Guadalajara Picks

This should be a straightforward assignment for the home side this weekend based on the strength of their form. Club America have excelled at both ends of the field already this season, and another victory to nil could be achieved against Guadalajara.