Last updated Aug 13, 4:19am ET

A huge showdown is set for the MLS in Illinois on Aug 16, as the playoff-chasing hosts bid to secure a significant win. You can find the odds and our Chicago vs. St. Louis picks here.

The Chicago Fire currently sit ninth in the Eastern Conference standings, and they could move to within two points of the top seven with a win on Saturday. Chicago will be aiming to extend their unbeaten sequence following a home draw against LAFC last time out.

St. Louis confidence should be high after a shock win over Nashville in the previous round. That victory ended a three-game losing sequence across all competitions.

Chicago vs. St. Louis Overview

StatInformation
Date & TimeSaturday, August 16, 2025 @ 8:30 PM ET
WhereSeatGeek Stadium, Illinois
How to WatchApple TV

Odds

Match ResultOdds
Chicago-172
Draw+370
St. Louis+388

Chicago vs. St. Louis Head-to-Head Record

TotalChicagoSt. LouisDraws
Wins3210
MLS Games2110
Goals844 

St. Louis recorded a first victory against the Fire in the most recent clash between the sides in May 2024. However, they have suffered losses in each of their two trips to Illinois.

Chicago Team News

The Fire will still be without long term absentee Chris Mueller on Saturday.

Possible Lineup

C. Brady (GK); A. Gutman, J. Elliott, C. Teran, L. Barroso, S. Oregel, D. D’Avilla, B. Gutierrez, P. Zinckermagel, H. Cuypers, J. Bamba

St. Louis Team News

St. Louis are unlikely to make many changes to the team that claimed a 3-1 success against Nashville last weekend.

Possible Lineup

R. Burki (GK); D. Padelford, F. Fall, T. Baumgartl, J. Orozco, A. Morales, E. Lowen, S. Jeong, T. Ostrak, M. Hartel, J. Klauss

Chicago vs. St. Louis Picks

Despite a rare win over Nashville last weekend, it will be hard to side with the visitors when making Chicago vs. St. Louis picks on Saturday.

The hosts have been in strong recent form as they bid to secure a playoff spot in the Eastern standings, and we find it challenging to overlook the prospect of a home victory this weekend.

Pick
Chicago Fire (-172)
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Alex Dudley
Alex Dudley

Sports Analyst and Betting Expert

Alex has over 15 years of experience in sports betting, specializing in soccer and horse racing. He uses his deep knowledge of markets and strategies to guide readers through disciplined and informed betting.

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