Saints vs Bills NFL Pick: 0-3 New Orleans Now Faces Josh Allen (Sep 28)

• In NFL Week 4 Saints-Bills, winless and overmatched New Orleans faces unbeaten Buffalo and Josh Allen
• New Orleans kept its first two games close, losing to the Cardinals and 49ers by a combined 12 points; against the Seahawks, they were blown out 44-13
• Buffalo has scored at least 30 points in its 3 games this season, and it could have been more against the Jets
• The Bills are a massive favorite, currently between 16.5 and 17 points

Do the Saints Need a Catchy Phrase About Getting Arch Manning Already?

For the Colts, it was “Suck for Luck” when Andrew Luck was coming out of Stanford.

For the Dolphins, it was “Tank for Tua” when Tua Tagovailoa was coming out of Alabama.

Will the Saints, who drafted Tyler Shough 40th overall in the 2025 NFL Draft and have second-year Spencer Rattler who has played reasonably well, look toward the 2026 draft and consider ensuring they get a high enough pick to take University of Texas QB and Louisiana native Arch Manning?

Larch for Arch?

Stanning for Manning?

Reasonable, grammatically correct ideas with the proper definitions of the words are welcome.

They’re 0-3 and the immediate future is bleak. To make it even more complex if they are thinking about Arch Manning is that the next Manning star QB has had early-season struggles for Texas.

The Saints put up a good fight in Weeks 1 and 2. They kept the games close against the Cardinals and 49ers, but in Week 3 were manhandled by the Seahawks. Seattle is not known for its offensive firepower, but put up 44 points without Zach Charbonnet. This magnifies New Orleans’ problems.

By now, they need to prepare to gauge the trade market to deal away Alvin Kamara, Demario Davis, Brandin Cooks, among others.

New Orleans is near the worst in the league in points scored and points allowed. They’re in the bottom half in allowing passing yards per game and 14th in defensive rushing yards allowed. They’re at zero in turnover differential.

The overwhelming likelihood is that Josh Allen, James Cook and the Bills’ offense will run up and down the field at will.

The Bills Have a Run of Heavily-Favored Games

On paper, the Bills should be 7-0 when they host the Chiefs in Week 9.

Of course, “any given Sunday,” blah blah blah.

After their Week 3 Thursday Night Football harder-than-expected slugfest over the Dolphins, Buffalo had 10 days to get ready for this four-week run where they play the Saints, Patriots, Falcons, and Panthers in the run up to KC.

Against the Saints, the Bills are favored by two TDs and a field goal.

Josh Allen has been masterful thus far completing 69 of 99 passes for 5 TDs and no interceptions. He has a 108.8 passer rating. He’s run for 114 yards on 24 carries and scored 2 TDs.

Running back James Cook is averaging 5.4 yards-per-carry and has 284 yards on 53 carries so far. Second-year wideout Keon Coleman is on the verge of stardom and by the end of the season might have supplanted Khalil Shakir and Dalton Kincaid as Allen’s first option downfield.

Buffalo needs to shore up its rush defense. They’re last in the league in yards allowed per game. The pass defense has been excellent, second in the NFL. They are +3 in takeaways and are averaging 34 points-per-game.

Injured Matt Milano and Ed Oliver could play this week.

Saints vs Bills Pick

Week 4 Saints-Bills is almost the equivalent of the University of Alabama playing the fictional Southwest Newman State in the Appalachian Mountains. That, however, does not mean the Bills will completely blow the Saints off the field to the tune of a 16.5-17-point spread.

Buffalo will run the ball effectively with Cook and pass early in the game to get control of the game. If Buffalo is leading by double-digits by the second half, Mitchell Trubisky and the backups will be in the game.

Rattler has been solid and Kamara is still a top-tier back who will help a contender if the Saints do the smart thing and trade him.

New Orleans will keep the game close for the first quarter before Buffalo overwhelms them and covers that heavy spread.