Published Dec 3, 7:32pm ET by
Keith McCarthy - Betting Preview Analyst and Sports Writer
Last updated Dec 3, 7:32pm ET
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The Bengals and Bills meet this week in what is now a signature AFC rivalry. Cincinnati took a major step forward last week but essentially needs to win out to have a chance at the playoffs.
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| Buffalo Bills | -5.5 (-105) |
| Cincinnati Bengals | +5.5 (-105) |
The Bengals stomped the Ravens in Baltimore on Thanksgiving, winning 32-14. The return of Joe Burrow, who had been out since Week 2, made an immediate impact for Cincinnati's offense. Unfortunately, they currently sit at 4-8 on the season, limiting their hopes of making the playoffs. Winning out would give them a chance, but it will be a difficult task. It won't start easy either, with this trip to Buffalo up next.
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YOSHI TD
— Cincinnati Bengals (@Bengals) November 28, 2025
📺: #CINvsBAL on NBC pic.twitter.com/lFU348UU2w
Buffalo got a much-needed bounce back win on Sunday after they lost two of the previous three games. Their defense was the standout, holding the Steelers to just 7 points. They made opposing QB Aaron Rodgers look even more out of his depth, holding him to 117 passing yards. On offense, the Bills were equally efficient. They'll aim to build on their recent success as they chase the Patriots in the AFC East.
JOSHUA FREAKIN' ALLEN‼️@JoshAllenQB x #ProBowlVote pic.twitter.com/vPOZG06nVV
— Buffalo Bills (@BuffaloBills) November 30, 2025
With Burrow back in the lineup for Cincinnati, this is sure to be an epic clash between two of the best QBs in the league. The Bengals looked like a completely different team in their win over the Ravens, giving them a chance to surge to another victory this week. That being said, the Bills also had an impressive win of their own last week. With the defense starting to heat up, Buffalo will be very tough to beat at home.
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Pick
Buffalo Bills -5.5
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