The Miami Hurricanes are looking to carry on their winning streak when they visit the Virginia Tech Hokies in Blacksburg. The all-time series between these teams is dominated by Miami, with a record of 26–15. We’ll see if the Hurricanes are capable of extending their dominance over this ACC rival.

The Louisville Cardinals are paying a visit to the SMU Mustangs in an ACC battle and their fourth all-time matchup. The Cardinals have never beaten SMU in their historic series (0–3), so they’ll be looking to earn their first-ever win against the Mustangs.

The Oklahoma Sooners will host the Missouri Tigers in an SEC clash with rivalry written all over it. Oklahoma leads the all-time series 67–25–5, but Missouri will be looking to earn their second straight victory over the Sooners.

#12 BYU heads to #25 Cincinnati for a crucial Big 12 battle, with the winner taking a major step toward improving their position in the conference title race. BYU and Cincinnati have faced each other only three times before, and the Cougars have won all three matchups.

The Pittsburgh Panthers head to Atlanta to face Georgia Tech in an ACC clash that’s sure to draw attention. This will be the 16th meeting between the two programs, with the Panthers holding the all-time series advantage at 11–4. Georgia Tech enters as the favorite with a -2.5 spread.

The USC Trojans pay a visit to Eugene this weekend in a high-stakes matchup against the Oregon Ducks. The last time USC traveled to Oregon, it didn’t end well for the Trojans. However, they still lead the all-time series with a 38-23-2 record.

Iowa Hawkeyes will pay a visit to Los Angeles Memorial Coliseum to battle USC in a ranked match that's sure to catch attention. Both teams are making a playoff push, however, if USC takes the victory, they'll be in a good position to cement themselves and meet their season goals. The all-time series between each other has Iowa with the 7-3 edge.

#10 Notre Dame will battle #24 Pittsburgh in a renewed rivalry this Saturday November 15th at noon ET. The Fighting Irish are on a 7-game winning streak, despite them losing their first two games this season. Pittsburgh is also on a winning streak, having 5 games won in a row, making this matchup a must watch game.

Texas and Georgia meet this week in what is now a new SEC rivalry. The Bulldogs are favored to continue their winning streak here, but they face a major challenge against the rested Longhorns.

Oklahoma and Alabama face off this week in a key battle. The Crimson Tide are seeking to add to their 8-game winning streak, while Oklahoma will attempt to pull off a major upset on the road.

The BYU Cougars will be hosting the Texas Tech Red Raiders in what promises to be a close match between two Big 12 teams currently ranked in the Top 10. This will be the second time these teams meet, giving BYU the slight edge from their previous game. The game will be played at the Jones AT&T Stadium.

The Vanderbilt Commodores will be visiting the Texas Longhorns in Austin for a Week 10 battle for SEC supremacy. Both teams have been playing excellent this season so far and this game will determine who continues their winning streak and who doesn't.