The Miami Hurricanes are visiting Pittsburgh at Acrisure Stadium with a chance to end the season on a high note heading into the CFP. It’s been three years since these teams last played, with Miami leading the historical series 29–12–1.

We have a banger with Vanderbilt visiting Tennessee in an in-state battle to close out their 2025 regular season campaign. The result of this game will determine what comes next for each team, as both have high hopes for their playoff aspirations. Tennessee leads the rivalry 79–32–5 across 119 meetings.

What’s known as “The Game” will be played at The Big House in Ann Arbor, with Ohio State visiting Michigan. Michigan leads this rivalry over 120 meetings with a 65–51–6 record. We’ll see what happens this time around, as the Buckeyes are out for revenge.

Mountain America Stadium in Tempe will be hosting a tight rivalry game between Arizona State and Arizona this week. Both teams are aiming to climb up the Big 12 standings, so a win here is crucial for both sides.

The Lone Star State is hosting a classic rivalry game, with undefeated Texas A&M visiting the Texas Longhorns. The game will be played the day after Thanksgiving at DKR–Texas Memorial Stadium. Get ready to enjoy an epic rivalry matchup with Playoff implications.

We all love a good, old-fashioned rivalry, right? Well, we’re getting one this weekend when the Georgia Bulldogs visit the Georgia Tech Yellow Jackets. The game will be played at Mercedes-Benz Stadium in Atlanta, with the Bulldogs holding a historic 72–41–5 lead in the series across 118 total meetings.

The Miami Hurricanes are looking to carry on their winning streak when they visit the Virginia Tech Hokies in Blacksburg. The all-time series between these teams is dominated by Miami, with a record of 26–15. We’ll see if the Hurricanes are capable of extending their dominance over this ACC rival.

The Louisville Cardinals are paying a visit to the SMU Mustangs in an ACC battle and their fourth all-time matchup. The Cardinals have never beaten SMU in their historic series (0–3), so they’ll be looking to earn their first-ever win against the Mustangs.

The Oklahoma Sooners will host the Missouri Tigers in an SEC clash with rivalry written all over it. Oklahoma leads the all-time series 67–25–5, but Missouri will be looking to earn their second straight victory over the Sooners.

#12 BYU heads to #25 Cincinnati for a crucial Big 12 battle, with the winner taking a major step toward improving their position in the conference title race. BYU and Cincinnati have faced each other only three times before, and the Cougars have won all three matchups.

The Pittsburgh Panthers head to Atlanta to face Georgia Tech in an ACC clash that’s sure to draw attention. This will be the 16th meeting between the two programs, with the Panthers holding the all-time series advantage at 11–4. Georgia Tech enters as the favorite with a -2.5 spread.

The USC Trojans pay a visit to Eugene this weekend in a high-stakes matchup against the Oregon Ducks. The last time USC traveled to Oregon, it didn’t end well for the Trojans. However, they still lead the all-time series with a 38-23-2 record.