Leagues Cup: Seattle vs. Santos Laguna Picks — Sounders to Build on Dominant MD1 Showing? (Aug 3)

The 2025 Leagues Cup couldn’t have gotten off to a better start for the Seattle Sounders, as they were rampant winners on matchday one. They will be hoping to maintain that form when they come up against Santos Laguna on Sunday.

The Sounders were at their dynamic best against Cruz Azul in midweek, smashing seven efforts past their hapless Mexican rivals. Six different players found the net in the dominant outing, with Pedro de la Vega netting twice.

Santos Laguna will be aiming to get their campaign back on track after throwing away a 1-0 lead in the final half an hour against the Colorado Avalanche on Thursday evening.

Seattle vs. Santos Laguna Overview

Odds

Seattle vs. Santos Laguna Head-to-Head Record

The Seattle Sounders were 1-0 winners against Santos Laguna in the Leagues Cup in 2021. That victory means that the Sounders have now avoided defeat in their last two against their Mexican rivals.

Seattle Team News

The Sounders will be without a trio of first-team stars this weekend. Stefan Frei remains absent due to a head injury, while Joao Paulo and Paul Arriola are both also ruled out.

Possible Lineup

A. Thomas (GK); N. Tolo, J. Ragen, Y. Gomez, A. Roldan, C. Roldan, O. Vargas, R. Kent, A. Rusnak, J. Ferreira, D. Musovski

Santos Laguna Team News

The Mexican side has no injury concerns ahead of this clash on Sunday. However, Carlos Acevedo will be absent after being sent off against the Avalanche on Thursday evening.

Possible Lineup

H. Holguin (GK); B. Amione, K. Balanta, I. Govea, R. Prieto, S. Mariscal, A. Vargas, D. Medina, J. Carrillo, C. Dajome, J. Ocejo

Seattle vs. Santos Laguna Picks

The Sounders were electric in their opening match of the Leagues Cup, and they will be heavily expected to maintain that strong attacking form this Sunday.

Santos Laguna will be without their first-choice goalkeeper, which could unsettle the backline this weekend. Therefore, we could see Seattle recording victory by at least a two-goal margin at Lumen Field.