Nashville SC vs. Inter Miami MLS Picks: Messi on Verge of Second Round (Nov 1)

Published Oct 29, 5:06am ET by

Alex Dudley - Betting Preview Analyst and Sports Writer

Last updated Oct 29, 5:06am ET

Pick status
Game Two in the Nashville SC vs. Inter Miami playoff series takes place on November 1. Find the odds and our picks here.

Credit: Shutterstock

Updated Oct 29, 5:06am ET

  • Inter Miami claimed a straightforward win in Game One of the series against Nashville SC
  • Lionel Messi scored two goals in the 3-1 home success last Saturday

The action in the MLS Playoffs continues this weekend, as Game Two in the series between Nashville and Inter Miami will be staged at Geodis Park.

Inter Miami made their dominance count in the opening clash between the sides last Saturday, with Lionel Messi scoring twice in a 3-1 victory.

Nashville offered little in the offensive areas of the field, accumulating just three shots on target. The odds will indicate that Inter Miami could be the first team to secure their spot in the second round.

Nashville SC vs. Inter Miami Overview Watch On: Apple TV

DATE & TIME

Saturday, November 1, 2025 @ 7:30 PM ET
Nashville SC
Geodis Park, Nashville
Inter Miami
GAME ODDS
BetOnline
Nashville SC +153
The Draw +275
Inter Miami +149

Pressure on Nashville SC

Nashville SC have been a regular player in the playoffs, but they have only reached the second round on two occasions since 2017.

Despite that, they will take confidence from their positive home record throughout the season when it comes to their Game Two aspirations.

They have been a dominant force at Geodis Park, winning eleven of their 17 matches, and scoring an average of 2.12 goals per game. However, they will need to come up with a game plan to stop Messi's influence this Saturday.

Possible Lineup
(4-3-3) Willis (GK); Najar, Zimmerman, Palacios, Lovitz; Yazbek, Tagseth, Acosta; Mukhtar, Surridge, Shaffelburg

Inter Bidding to Secure Spot in Second Round

Inter Miami have been the front-runners for MLS Cup glory throughout the season, and their chances would have increased following a straightforward game one success last Saturday.

However, wins on the road have been harder to achieve for Lionel Messi's side. Inter have won just eight of their 17 away from Chase Stadium.

Meanwhile, they have conceded a lofty average of 1.71 goals per game. Despite that, their recent form sees them hold a clear advantage this weekend.

Possible Lineup
(4-4-2) Novo (GK); Fray, Allen, Falcon, Alba; Allende, Busquets, De Paul, Rodriguez; Messi, Suarez
Nashville vs. Inter Miami Fire Head-to-Head Record
TOTAL Nashville Inter Miami DRAWS
Games 17 4 8 5
Goals 50 23 27

Nashville SC vs. Inter Miami Picks

Inter Miami have now recorded victories in each of their last six matches against Nashville SC. That is an incredibly hard pattern to overlook when making Nashville SC vs. Inter Miami picks.

Therefore, we will be siding with the visitors to secure their spot in the second round of the playoffs on Saturday.

Pick
Inter Miami (+149)
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