Leagues Cup Outright Winner Odds, Preview, and Picks (2025)

Teams from Mexico and the United States will collide over the next two weeks, as the 2025 edition of the Leagues Cup gets underway on July 29.

A total of 36 teams will be involved in the new-look format, where each team will play three matches to determine the sides that qualify for the knockout round. The Columbus Crew are the defending champions, but how do their chances appear based on the odds?

Odds

Leagues Cup 2025 Information

How Does The Competition Work?

Unlike previous editions of the Leagues Cup, the 2025 edition will follow a different format.

Phase One will see each team play three matches against clubs from the other league, meaning MLS teams will play all opening round fixtures against Mexican teams.

The top four from each league will qualify for the next round.

Leading Leagues Cup Contenders

Inter Miami

Lionel Messi’s Inter Miami will be among the leading contenders this summer, as they bid to regain the title that they won in 2023.

Inter Miami comes into the tournament in excellent recent form, and the arrival of Rodrigo De Paul strengthens their options in the middle of the park.

However, their defensive record does raise concerns, especially when they come up against strong Mexican sides.

Columbus Crew

The reigning Leagues Cup champions will have a strong chance of retaining their honor in 2025.

Columbus have been a standout team in the Eastern Conference this season, and they have registered victories in two of their last three matches.

The Crew have been excellent at both ends of the field this season, scoring 1.63 goals per game and allowing just 1.38 per 90.

Club America

MLS teams have dominated the last two editions of the Leagues Cup, but Club America could be an outstanding chance to end that success.

Club America have won once in their opening two matches this season. Their offensive quality makes for interesting reading, as they have already netted an average of two goals per game.

However, they will need to make a quick start if they are to enhance their qualification aspirations.

Leagues Cup 2025 Outright Winner Pick

FC Cincinnati have been one of the standout teams in the MLS this season, winning each of their last two matches without conceding.

Their defensive quality could make them a force at the Leagues Cup in 2025, as they have allowed just 1.29 efforts per game.