Oilers vs. Senators NHL Picks: Visitors Aiming to End Three-Game Losing Sequence (Oct 21)

Published Oct 21, 3:30am ET by

Alex Dudley - Betting Preview Analyst and Sports Writer

Last updated Oct 21, 3:30am ET

Pick status
Competitive NHL action is set for Ottawa on Oct 21. You can find the latest odds and our Oilers vs. Senators picks here.

Credit: Shutterstock

Updated Oct 21, 3:30am ET

  • Edmonton Oilers have suffered defeats in their last three games in the NHL
  • Ottawa Senators bidding to bounce back from a recent loss

Interesting action is set for theΒ NHLΒ on Oct 21, as the Senators host the Oilers. Find our picks here.

The Edmonton Oilers will be hoping to end a three-game losing sequence. Meanwhile, the Ottawa Senators are chasing a second win in three games.

Ottawa Senators vs. Edmonton Oilers Overview Watch On: ESPN+

DATE & TIME

Tuesday, October 21, 2025 @ 7:00 PM ET
Ottawa Senators
Canadian Tire Centre, Ottawa
Edmonton Oilers
GAME ODDS
BetOnline
Ottawa Senators +121
Edmonton Oilers -137

Senators Aiming to Respond

The Ottawa Senators have endured a mixed start to the campaign, but their attacking players have flourished in recent games.

They have scored seven goals across their last two games, which included four in a loss against the New York Islanders last weekend.

Despite an eye-catching offensive display, the Senators dropped to the defeat after conceding twice in the final period. Tim Stutzle and David Perron both scored goals in the loss.

Oilers Bidding to Break Losing Run

Despite making an impressive start to the season, the Edmonton Oilers have now lost each of their last three games.

Defensive questions will be asked of the team after allowing 13 goals across that period. Last time out, they were beaten 4-2 by the Detroit Red Wings.

The Oilers allowed three goals in the second period, which was ultimately costly. Leon Draisaitl and Noah Philp scored the goals in reply.

Oilers vs. Senators Head-to-Head Record
TOTAL Oilers Senators DRAWS
WINS 61 24 33 -
GOALS 373 170 203

Oilers vs. Senators NHL Picks

It has been a challenging period for the Oilers, but this could be a perfect opportunity to get back on track.

If they are able to sort out their defensive issues, they look like the standout win angle. Their chances are enhanced after winning 58.6% of their away games against the Senators.

Pick
Edmonton Oilers (-137)
New Player Bonus
50% up to $1000