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Rams vs Jaguars NFL Pick: Jags Aim for Bounce Back Win in London (Oct 19)

Published Oct 13, 7:08pm ET by

Keith McCarthy - Betting Preview Analyst and Sports Writer

Last updated Oct 13, 7:08pm ET

Pick status
matthew stafford Rams

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Updated Oct 13, 7:11pm ET

  • The Rams improved to 4-2, following their 17-3 victory over the banged-up Ravens.
  • Jacksonville had their win streak snapped by the Seahawks on Sunday, losing 20-12.
  • These two teams last met on December 5, 2021, in a game that the Rams won 37-7.

The Rams and Jaguars face off this week in a clash between two playoff hopefuls. Both enter this game at 4-2, aiming to rise to 5-2 and take a step closer to a postseason bid. Jacksonville lost last week to Seattle and is aiming to bounce back, while the Rams seek to start a winning streak.

Jacksonville Jaguars vs. Los Angeles Rams Overview Watch On: NFL Network

DATE & TIME

SUNDAY, OCTOBER 19, 2025 @ 9:30 AM ET
Jacksonville Jaguars
WEMBLEY STADIUM
LONDON, ENGLAND
Los Angeles Rams
GAME ODDS
BetOnline
Jacksonville Jaguars +2.5 (-105)
Los Angeles Rams -2.5 (-110)

Rams Aim to Keep Up Winning Ways

The Rams improved to 4-2 following their win over the Ravens. They held their opposition to just 3 points, a combination of their stout defense and Baltimore's lack of starting QB Lamar Jackson. Los Angeles must continue winning to stay afloat in a very competitive NFC West division. They'll need to overcome any jetlag from the 5,500 mile trip from LA to London as they face a Jaguars team with just as many wins.

Jaguars Seek Bounce Back Overseas

Jacksonville was unable to increase their winning streak to four games against the Seahawks. Despite being at home, their offense continued to be inconsistent as they finished the game with just 12 points. The Jaguars get another shot at the NFC West this week, heading to London once again. This time, they'll face off with the 4-2 Rams who are likely to keep testing Jacksonville's offense with their capable defense.

Injury / Suspension
PLAYER STATUS
TE Brenton Strange - Jacksonville Jaguars INJURED

Rams vs Jaguars NFL Pick

The Jaguars have more experience playing in London than any other team and over 1,000 fewer miles to travel to get there. That will give them somewhat of an advantage over the Rams, who are traveling across the globe to play a game at 6:30 AM LA local time. Still, even with that advantage, Los Angeles is favored here. With both offenses likely to come out sluggish, the Rams defense is the most reliable asset.

Pick
Los Angeles Rams -2.5
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