Packers vs Lions NFL Pick: Will Detroit Remain Dominant In This Head-To-Head Matchup (Sep 7)
One of the games on Sunday’s NFL slate features the Green Bay Packers hosting the Detroit Lions. Who has the edge in...

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Last updated Sep 1, 5:45pm ET
- The Green Bay Packers finished third in their division with an 11-6 record in 2024.
- The Detroit Lions topped the NFC North Division, finishing with a win-loss record of 15-2.
- These teams previously squared off on Dec. 5, 2024, with the Lions winning by a narrow 34-31 margin.
One of the games on Sunday’s NFL slate features the Green Bay Packers hosting the Detroit Lions. Who has the edge in our Packers vs Lions pick?
Packers Aim to Become an NFC Defensive Powerhouse
Green Bay was 11-4 through its first 15 games of the season. Unfortunately, the team concluded the 2024 campaign with back-to-back losses against the Vikings and Bears.
Then, the green and gold were eliminated in the wildcard round of the playoffs, falling to the Eagles 22-10. Green Bay hopes the addition of Micah Parsons will help this group take the next step on the defensive side of the ball.
Detroit Looks To Finish What It Started
Meanwhile, the Lions finished with a 15-2 record, the best in franchise history. Unfortunately, the feel-good story from their record-breaking season was short-lived, as they were upended by the Washington Commanders 45-31 in the postseason’s divisional round.
With the departure of both coordinators, including Ben Johnson going to Chicago, Detroit is out to prove that last year’s 15-win season was not a fluke.
Packers vs Lions NFL Pick
Green Bay enters this divisional contest as a 2.5-point favorite. Here are a few betting trends to consider for both teams ahead of this Week 1 matchup.
- The Lions are 14-2 straight-up (SU) in their last 16 games.
- Detroit is 12-4 ATS in its previous 16 outings against Green Bay.
- The Packers have won 10 of their last 14 games at Lambeau Field.
- Green Bay is just 2-6 ATS in its previous eight home matchups against the Lions.
Given the trends, look for the Lions to emerge victorious, albeit by a small margin.
Pick
Detroit Lions
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