Lions vs Buccaneers NFL Pick: Can Detroit Notch Another Dominant Win At Home? (Oct 20)

Published Oct 15, 7:20pm ET by

James Tillman - Betting Preview Analyst and Sports Writer

Last updated Oct 15, 7:20pm ET

Pick status
The Lions look to improve to 5-2 when they host the Buccaneers on Monday Night Football.

Shutterstock

Updated Oct 15, 7:20pm ET

  • The Detroit Lions are 4-2 after a 30-17 loss to the Kansas City Chiefs.
  • Tampa Bay improved to 5-1 after beating the San Francisco 49ers 30-19.
  • These squads previously faced off on Sep. 15, 2024, with the Buccaneers claiming a 20-16 victory.

One of the games on Monday's NFL slate features the Detroit Lions hosting the Tampa Bay Buccaneers. Who has the edge in our Lions vs Buccaneers pick?

Detroit Lions vs. Tampa Bay Buccaneers Overview Watch On: ABC/ESPN

DATE & TIME

MONDAY, OCTOBER 20, 2025 @ 7:00 PM ET
Detroit Lions
Ford Field
Detroit, MI
Tampa Bay Buccaneers
GAME ODDS
BetOnline
Detroit Lions -5.5 (-110)
Tampa Bay Buccaneers +5.5 (-110)

Lions Aim To Get Back Into The Win Column

The game was close in the first half, as Detroit trailed the Chiefs 13-10 at the end of the first 30 minutes. But the team boasting the league's top offense produced only seven points after the break and was defeated by a 30-17 margin.

Jared Goff finished 23 of 29 for 203 yards, along with two touchdowns. Jahmyr Gibbs ran for 65 on 17 rushing attempts, and Jameson Williams caught six passes totaling 66 yards.

Tampa Bay Eyeing Its Second Three-Game Win Streak

Although the 49ers were missing several key players, the Buccaneers led by a slim 20-19 lead in the third quarter. Tampa Bay pulled away, though, courtesy of Baker Mayfield's 45-yard TD pass to Tez Johnson.

With a chance to tie the score, Mac Jones threw an interception from Tampa Bay's 33-yard line. The miscue resulted in the Buccaneers tacking on another field goal, providing the final margin of this contest.

Mayfield completed 17 of 23 passes for 256 yards with two touchdowns. Kameron Johnson had four catches for 64 yards, and Rachaad White added 65 rushing yards.

Lions vs Buccaneers NFL pick

Following their double-digit loss against KC, the Lions enter this contest as a 5.5-point favorite. Here's a look at what you need to know for both teams ahead of this Week 7 matchup.

  • The Lions are 16-4 straight-up (SU) in their last 20 games.
  • Detroit has covered the spread four times in its previous five outings.
  • The Buccaneers are 8-3 in their last 11 road games against the Lions.
  • Tampa Bay is 5-12 ATS in its previous 17 matchups against Detroit.

Detroit is 2-3 in the previous five meetings in this series. However, in their two home wins, the Lions have outscored their opponents by an 86-31 margin. With that in mind, look for Detroit to come out on top in a close one.

Pick
Detroit Lions
New Player Bonus
50% up to $1000
Further Reading
Portland vs. San Diego MLS Picks: Timbers to Secure Top-Seven Finish? (Oct 18)
Portland vs. San Diego MLS Picks: Timbers to Secure Top-Seven Finish? (Oct 18)
Portland Timbers need a win on the final day to secure seventh in the Western Conference San Diego could yet finish top of the...
Bruins vs. Golden Knights NHL Picks: Competitive Match-Up Set for Sin City (Oct 16)
🏒
Bruins vs. Golden Knights NHL Picks: Competitive Match-Up Set for Sin City (Oct 16)
Vegas Golden Knights have gone 2-0-2 at the start of the season Boston Bruins chasing a response after a dramatic loss on Sunday Competitive...
Hurricanes vs. Ducks NHL Picks: Perfect Visitors to go 4-0-0? (Oct 16)
🏒
Hurricanes vs. Ducks NHL Picks: Perfect Visitors to go 4-0-0? (Oct 16)
Carolina Hurricanes have gone 3-0-0 to sit top of the Metropolitan Division Anaheim Ducks improved to 2-1-0 after a win on Tuesday One of...
Rangers vs. Maple Leafs NHL Picks: Travelling Rangers Chasing Return to Form (Oct 16)
🏒
Rangers vs. Maple Leafs NHL Picks: Travelling Rangers Chasing Return to Form (Oct 16)
New York Rangers have gone 2-3-0 at the start of the 2025-26 NHL season Toronto Maple Leafs have won two of their opening four...