Chargers vs Chiefs NFL Pick: Mahomes and Chiefs Face Rare Challenge (Dec 14)

Published Dec 10, 5:46pm ET by

Keith McCarthy - Betting Preview Analyst and Sports Writer

Last updated Dec 10, 5:46pm ET

Pick status
Patrick Mahomes at Kansas City Chiefs game.

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Updated Dec 10, 5:48pm ET

  • The Chargers took down the Eagles in overtime on Monday night, defeating them 21-18.
  • Kansas City struggled on offense once again, losing to the Texas 20-10 and falling to 6-7.
  • These two teams last faced off way back in Week 1, in a game that the Chargers won 27-21.

The Chargers and Chiefs meet this week in a divisional clash. Kansas City is in a rare position at 6-7, desperately needing a win in this game to stay alive in a very competitive AFC Wild Card race.

Kansas City Chiefs vs. Los Angeles Chargers Overview Watch On: CBS

DATE & TIME

SUNDAY, DECEMBER 14, 2025 @ 1:00 PM ET
Kansas City Chiefs
ARROWHEAD STADIUM
KANSAS CITY, MO
Los Angeles Chargers
GAME ODDS
BetOnline
Kansas City Chiefs -4.5 (-105)
Los Angeles Chargers +4.5 (-105)

Chargers Inch Closer to Playoff Bid

The Chargers won another key matchup on Monday night, climbing to 9-4 on the season. They've now won 5 of their last 6 games and are closing in on a playoff spot. Los Angeles remains two games out of first place in a competitive AFC West, but still has time to make a push for the division title. They will look to take advantage of the Chiefs' struggles and earn a season sweep over them for the first time since 2013.

Chiefs in Rare Danger of Elimination

The Chiefs are having an uncharacteristic season for the Patrick Mahomes era. They fell to 6-7 following Sunday's defeat, lowering their postseason chances to below 30%. Kansas City needs to finish 4-0 to have any realistic shot, putting on a lot of pressure as they face a rematch with a Chargers team that beat them once already this year. The offense will be under a microscope once again as they fight elimination.

Chargers vs Chiefs NFL Pick

The Chargers snapped a 7-game losing streak to the Chiefs back in Week 1, but have still gone 4-19 against them since 2013. Coupled with Kansas City's homefield advantage and desperation for a win in this game, and Los Angeles faces an uphill battle. That being said, they've been the better team for the entirety of this season. Even if the Chiefs snag the win, expect this game to stay within a field goal margin.

Pick
Los Angeles Chargers +4.5
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