Cardinals vs Cowboys NFL Pick: NFC Squads Clash in MNF Battle (Nov 3)

Published Oct 31, 10:24pm ET by

Keith McCarthy - Betting Preview Analyst and Sports Writer

Last updated Oct 31, 10:24pm ET

Pick status
Packers will play Rams in the NFL on October 6

Updated Oct 31, 10:25pm ET

  • The Cardinals were on their bye last week and are currently amidst a 5-game losing streak.
  • Dallas struggled defensively once again against the Broncos, giving up 44 points in the loss.
  • These two teams last faced off on September 24, 2023, in a game that the Cardinals won 28-16.

The Cardinals and Cowboys face off this week in what should be a high-scoring clash. Both teams have struggled to find consistency on defense. Dallas aims to change that back at home.

Dallas Cowboys vs. Arizona Cardinals Overview Watch On: ABC/ESPN

DATE & TIME

MONDAY, NOVEMBER 3, 2025 @ 8:15 PM ET
Dallas Cowboys
AT&T STADIUM
ARLINGTON, TX
Arizona Cardinals
GAME ODDS
BetOnline
Dallas Cowboys -2.5 (-105)
Arizona Cardinals +2.5 (-105)

Cardinals Face Uphill Battle

The Cardinals started this season promising at 2-0, but have since lost five consecutive games. They were on a bye last week, giving some time to address the issues that have tanked their postseason odds. A portion of their struggles have been due to injuries, which the bye week gave some time to mend. Even at closer to full strength, Arizona will need to bring everything they have to avoid another loss this week.

Cowboys Defense Still in Shambles

The Cowboys continued to have massive defensive struggles in their 44-24 defeat to the Broncos. It's been no question that Dallas has had one of the worst defenses in the league since their decision to trade Micah Parsons. The Cowboys are still on the playoff bubble, but that decision is starting to be more and more glaring. They really need to avoid being the team to snap Arizona's losing streak on Monday night.

Injury / Suspension
PLAYER STATUS
RB James Conner - Arizona Cardinals INJURED
RB Miles Sanders - Dallas Cowboys INJURED

Cardinals vs Cowboys NFL Pick

This game is likely to be high scoring, especially if Kyler Murray returns from injury as is currently expected. Arizona is desperate for a win and could test the Cowboys by running up the score on their defense. That being said, Dallas had been improving defensively before last week and holds a notable advantage at home. With their own capable offense, the Cowboys should be able to take the victory here.

Pick
Dallas Cowboys -2.5
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