#14 Vanderbilt vs #19 Tennessee NCAAF Pick: In-State SEC Showdown at Neyland (Nov 29)

Published Nov 28, 10:27am ET by

Gabriel Kozlow - Betting Preview Analyst and Sports Writer

Last updated Nov 28, 10:27am ET

Pick status
Oklahoma State will play BYU in the NCAAF on October 18

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  • Last week, #14 Vanderbilt (9-2) beat Kentucky with a 45-17 score.
  • #19 Tennessee (8-3) are also coming of a 31-11 win against Florida.
  • Their last matchup was on November 30th, 2024, with the Volunteers beating the Commodores 36-23.

We have a banger with Vanderbilt visiting Tennessee in an in-state battle to close out their 2025 regular season campaign. The result of this game will determine what comes next for each team, as both have high hopes for their playoff aspirations. Tennessee leads the rivalry 79–32–5 across 119 meetings.

TENNESSEE VOLUNTEERS vs. VANDERBILT COMMODORES Overview Watch On: ESPN

DATE & TIME

SATURDAY, NOVEMBER 29, 2025 @ 3:30 PM ET
TENNESSEE VOLUNTEERS
Neyland Stadium
Knoxville, TN
VANDERBILT COMMODORES
GAME ODDS
BetOnline
TENNESSEE VOLUNTEERS -145
VANDERBILT COMMODORES +125

Commodores Fighting to Stay in the CFP Mix

Vanderbilt has had a solid season so far and will be looking to continue its success into bowl season. So far this year, they’ve beaten #11 South Carolina, #10 LSU and #15 Missouri, and now face a final ranked test against their #19 Tennessee rivals. The Commodores have won 4 of their last 5 games, so they carry solid momentum heading into Neyland Stadium.

ALSO SEE: #1 Ohio State vs #15 Michigan NCAAF Pick (Nov 29)

Vanderbilt’s main focus will be on its offense, as they currently rank 9th in points per game (38.9), 16th in passing yards (283.9 per game) and 19th in total yards (458.2 per game). This is thanks to their multifaceted QB, Diego Pavia, who has 26 passing TDs and 8 rushing TDs this season.

Volunteers Looking to Play Spoiler at Home

The Volunteers will be excited to host their in-state rivals with a chance to end the season with an identical record. Currently, Tennessee is 8–3 overall and 4–3 in SEC play, sitting just one game behind the Commodores. They enter the game as slight favorites with a -2.5 spread, making this a likely tight matchup.

Tennessee is also a force on offense, ranking 4th in total yards per game and 4th in total points per game. Joey Aguilar, their star QB, is the main reason they have such a high-powered offense, as he has already thrown for 3,145 passing yards with 23 touchdowns so far.

#14 Vanderbilt vs #19 Tennessee NCAAF Pick

Both teams are efficient on offense, so we expect a very high scoreline in this game. There is a reason why the over/under is a whopping 66.5. As mentioned, the home-team Volunteers are favorites at -2.5 with a moneyline of -145. The visiting Commodores have a moneyline of +125.

Tennessee hasn’t been able to beat any of its ranked matchups this year, so we don’t expect this to be any different. That’s why our recommended pick is Vanderbilt +2.5 (road underdog). Our second recommendation is Over 66.5, as we expect a barrage of points this weekend.

Pick
Vanderbilt +2.5
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