Penn State vs Clemson NCAA Pick: 2025 Pinstripe Bowl at Yankee Stadium (Dec 27)

Tigers riding 4-Game Win Streak

Published Dec 22, 11:52pm ET by

Gabriel Kozlow - Betting Preview Analyst and Sports Writer

Last updated Dec 22, 11:52pm ET

Pick status
Oklahoma State will play BYU in the NCAAF on October 18

Shutterstock

  • Penn State (6-6) beat Rutgers in their last game with a 40-36 score.
  • Clemson (7-5) also ended up winning with a 28-14 score versus South Carolina.
  • These teams last played back 1988 in the Citrus Bowl, with Clemson winning 35-10.

We have none other than the Pinstripe Bowl being played in Yankee Stadium between Penn State and Clemson. This will be the 2nd time these team match up together, with the first game happening more than 35 years ago.

CLEMSON TIGERS vs. PENN STATE NITANNY LIONS Overview Watch On: ABC

DATE & TIME

SATURDAY, DECEMBER 27, 2025 @ 12:00 PM ET
CLEMSON TIGERS
Yankee Stadium
Bronx, NY
PENN STATE NITANNY LIONS
GAME ODDS
BetOnline
CLEMSON TIGERS -170
PENN STATE NITANNY LIONS +142

Big Ten Squad Looking to Run Through Tigers

The Penn State Nittany Lions had a mediocre season with a 6-6 record, but still managed to get the invite to the Pinstripe Bowl. They saved face this season, ending the campaign on a 3-game win streak, which was focused on mostly running the football instead of passing.

Speaking of ruuning the football, Keyton Allen, their star RB, rushed for 1,303 yards and 15 TDs this season. They'll need a top performance from their team to clear up space and let Allen do his thing this game. Penn State are favorites -1.5 this game.

Clemson didn't have the best start this season with a 1-3 record; however, they managed to turn it around and end the season on a 7-5 record. They've won 6 of their last 8 games, plus have a 4-game win streak.

This will be the Clemson Tigers' 21 straight bowl appearance and 52 all time participation. They had great support from their QB, Cade Klubnik, along with a balanced offense where they averaged around 29 points per game.

Penn State vs Clemson NCAA Pick

Both teams have the momentum coming into this game, but the Tigers are slightly favs at -3 over the Nittany Lions. The over/under is 48.5 with an Moneyline of -170 for Clemson and +142 for Penn State.

This game had Penn State starting as favorites, however the spread switched up and now has Clemson as favorites. Our recommended pick is for the Clemson Tigers at -3.

Pick
Clemson -3
New Player Bonus
50% up to $1000