#1 Ohio State vs #15 Michigan NCAAF Pick: The Game at The Big House (Nov 29)

Published Nov 27, 12:12pm ET by

Gabriel Kozlow - Betting Preview Analyst and Sports Writer

Last updated Nov 27, 12:12pm ET

Pick status
Ohio State Buckeyes Football

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  • Last week, #1 Ohio State (11-0) smashed Rutgers with a 42-9 win.
  • #15 Michigan (9-2) won their 5th straight with a 45-20 victory over Maryland.
  • Their last matchup was on November 30th, 2024, with Michigan edging the Buckeyes 13-10.

What’s known as “The Game” will be played at The Big House in Ann Arbor, with Ohio State visiting Michigan. Michigan leads this rivalry over 120 meetings with a 65–51–6 record. We’ll see what happens this time around, as the Buckeyes are out for revenge.

MICHIGAN WOLVERINES vs. OHIO STATE BUCKEYES Overview Watch On: FOX

DATE & TIME

SATURDAY, NOVEMBER 29, 2025 @ 12:00 PM ET
MICHIGAN WOLVERINES
Michigan Stadium
Ann Arbor, MI
OHIO STATE BUCKEYES
GAME ODDS
BetOnline
MICHIGAN WOLVERINES +320
OHIO STATE BUCKEYES -425

Undefeated Buckeyes Chasing Revenge Game

Another year, another great Ohio State season. Currently undefeated and looking to close out the regular season without a loss, they’ll need to run through the Wolverines. The Buckeyes enter this game as heavy favorites with a -9.5 spread, but need to watch out, as Michigan has been playing outstanding football lately.

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Top-rated QB Julian Sayin already has 2,832 passing yards, 27 TDs, and only 4 interceptions so far. His main target has been Jeremiah Smith (potentially injured), with 69 receptions and 10 TDs this year, making him one of the top receivers in the nation. Both will need to be on their A-game to get the win this weekend.

Wolverines Look To Extend Win Streak

Michigan’s sole purpose this week is to get a win and ruin Ohio State’s perfect season. This, in turn, would help them climb the Big Ten standings and position themselves for a playoff push. They are currently on a five-game winning streak and will look to make it six behind a battle-ready home crowd.

Last year’s top recruit, first-year QB Bryce Underwood, has had a shaky season so far but has steadily improved as the weeks go by. Their running back, Jordan Marshall, is expected to return from injury for this game, providing much-needed support on the ground to help create a more dynamic offensive attack.

#1 Ohio State vs #15 Michigan NCAAF Pick

This will be “The Game”, where Ohio State looks to overwhelm Michigan on the scoreboard and stay undefeated this season. The Buckeyes are favorites at -9.5 on the spread with a 43.5 over/under. The moneyline is -425 for Ohio State and +320 for Michigan.

We trust that Ohio State will win this game, but can they cover the spread against a motivated Michigan team? We think they’ll win, but by a close margin, which is why we recommend taking the Wolverines +9.5 for this game.

Pick
Michigan +9.5
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