Syracuse vs #4 Duke NCAAB Pick: Blue Devils Look to Stay Hot at Cameron (Feb 16)

Published Feb 15, 10:22pm ET by

Gabriel Kozlow - Betting Preview Analyst and Sports Writer

Last updated Feb 15, 10:22pm ET

Pick status
Warriors will play the Trail Blazers in the NBA on Oct 23

Updated Feb 15, 10:26pm ET

  • Syracuse (15-11) beat SMU by a 79-78 buzzer beater win.
  • #4 Duke (23-2) beat Clemson at home with a 67-54 win.
  • The all-time series has Duke leading with a 17-6 record.

Cameron Indoor Stadium in Durham is in for a treat as the Syracuse Orange visit the Duke Blue Devils on Monday night. Duke is currently ranked No. 4 in the nation and has won 10 straight games against the Orange.

DUKE BLUE DEVILS vs. SYRACUSE ORANGE Overview Watch On: ESPN

DATE & TIME

MONDAY, FEBRUARY 16, 2026 @ 7:00 PM ET
DUKE BLUE DEVILS
Cameron Indoor Stadium
Durham, NC
SYRACUSE ORANGE
GAME ODDS
BetOnline
DUKE BLUE DEVILS -5000
SYRACUSE ORANGE +1500

Orange Desperate to Turn Things Around

Syracuse has definitely had an interesting season so far, currently 15–11 overall and 6–7 in ACC play. They’ve won their last two games, including one in double overtime against California, and another on a buzzer-beating winner against SMU. They’ll be trying to make it three straight, but they need to overcome a +20.5 underdog point spread against Duke on the road.

Their star player, freshman forward Donnie Freeman, is averaging 17.6 PPG and 7.2 RPG on 48.8% shooting. It would also be great if they gave decent minutes to Kiyan Anthony, Carmelo Anthony’s son, as an investment for the future, as he looks to have massive potential.

Duke Look to Extend their Dominance

Duke is having a great season so far, leading the ACC race with a 23–2 record. They are even better at home, with 16 straight home wins and a 60–3 record at Cameron Indoor Stadium under head coach Jon Scheyer. Their last loss came on the road against their rivals, UNC, in a 3-point defeat.

An interesting stat is that Duke is the second-tallest team in college basketball, which helps explain why they are elite in rebounding, blocks, and overall defense. Cameron Boozer is leading the way, ranking in the top 5 nationally in scoring and top 15 in rebounding.

Syracuse vs #4 Duke NCAAB Pick

We all know that Duke will very likely win this game — it’s really a question of whether they can cover the -20.5 spread. The over/under is 143.5, and there is a moneyline of -5000 for Duke and +1500 for Syracuse.

Importantly, Duke at home is beating teams by an average of 24.6 points per game. This is why we are taking Duke -20.5 to cover the spread as our recommended pick.

Pick
Duke Blue Devils -20.5
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