#20 Clemson vs #4 Duke NCAAB Pick: ACC Battle in Durham (Feb 14)

Published Feb 13, 2:29pm ET by

Gabriel Kozlow - Betting Preview Analyst and Sports Writer

Last updated Feb 13, 2:29pm ET

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Updated Feb 13, 2:48pm ET

  • #20 Clemson (20-5) is coming off a 66-76 loss to Virginia Tech.
  • #4 Duke (22-2) bounced back with a 70-54 win versus Pittsburgh.
  • The all-time series record has Duke dominating 115-34.

Cameron Indoor Stadium in Durham, has the Duke Blue Devils hosting the Clemson Tigers for an intense ACC battle. This will be a Top-20 clash between two teams who are looking to fine tune their team heading into March Madness next month.

DUKE BLUE DEVILS vs. CLEMSON TIGERS Overview Watch On: ESPN

DATE & TIME

SATURDAY, FEBRUARY 14, 2026 @ 12:00 PM ET
DUKE BLUE DEVILS
Cameron Indoor Stadium
Durham, NC
CLEMSON TIGERS
GAME ODDS
BetOnline
DUKE BLUE DEVILS -1100
CLEMSON TIGERS +700

Tigers Chasing Statement Win

Clemson is coming off a loss in their last game against a mediocre Virginia Tech, so they’ll need to prove that was a fluke by putting in a strong performance on the road. Clemson is close behind Duke in the ACC standings, currently 10–2 in conference with a 20–5 overall record.

Their defense is what stands out the most, as they allow only 64.6 points per game to opponents (a top-15 defense). They are led by RJ Godfrey on offense, while Carter Welling anchors the defense with 5.7 RPG. So far this season, they have beaten SMU, Syracuse, Boston College, California, and Notre Dame.

Blue Devils to Let Boozer Lead the Way

The Duke Blue Devils have only lost twice this season, carrying a 22–2 overall record and 11–1 in the ACC. They are coming off a win against Pittsburgh after a tense loss to their bitter rivals, the Tar Heels. Their playing style this year is built on elite defense, efficient scoring, and a top-tier talent in Cameron Boozer.

Boozer is leading the team with 23.0 PPG, 10.0 RPG, and 4.0 APG, making him the standout player on the squad. Aside from him, they get strong support from the perimeter with Isaiah Evans, who is averaging 14 PPG, and Patrick Ngongba II, who leads the team with 1.3 BPG.

#20 Clemson vs #4 Duke NCAAB Pick

Duke is playing at home today and is a -11.5 favorite to beat Clemson. The over/under is 133.5, and the moneyline is Duke -1100 and Clemson +700.

Clemson hasn’t fared too well against ranked teams this season, and Duke is looking great so far. Our recommended pick is Duke -11.5 on the spread to win this game.

Pick
Duke Blue Devils -11.5
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