Sixers vs Pistons NBA Pick: Will Detroit Stay Hot Against Philly? (Apr 4)

Published Apr 4, 12:50am ET by

James Tillman - Betting Preview Analyst and Sports Writer

Last updated Apr 4, 12:50am ET

Pick status
The Sixers hope to upend the Pistons when these teams clash on Saturday night.

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  • The Sixers are 43-34 following a 115-103 victory against the Minnesota Timberwolves.
  • Meanwhile, Detroit is 56-21 and leads the East.
  • These teams previously met on Mar. 12, with the Pistons winning 131-109.

One of the games on Saturday's NBA slate features the Philadelphia 76ers hosting the Detroit Pistons. Who has the edge in our Sixers vs Pistons pick?

Philadelphia 76ers vs. Detroit Pistons Overview Watch On: NBA TV

DATE & TIME

SATURDAY, APRIL 4, 2026 @ 7:00PM ET
Philadelphia 76ers
Xfinity Mobile Arena
Philadelphia, PA
Detroit Pistons
GAME ODDS
BetOnline
Philadelphia 76ers +112
Detroit Pistons -138

The Sixers are seeking their third straight win

Following a 10-point loss to the Pistons, Philadelphia has won its last two games. This includes a 115-103 victory against the Minnesota Timberwolves on Friday night.

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The Sixers flipped a six-point halftime deficit into a 12-point advantage through three quarters. Minnesota got within six points in the fourth before Kelly Oubre Jr. put the game away with consecutive 3-point buckets.

Paul George spearheaded a scoring effort in which five players reached double figures. He scored a team-high 23 points, along with six rebounds and six assists. Tyrese Maxey registered 21 points, eight assists, and six rebounds.

Detroit looks to extend its win streak to three games

After an overtime loss to Oklahoma City, the Pistons enter this matchup amid a two-game win streak, including a 113-108 victory against Minnesota on Thursday.

Detroit trailed by a point through the first 36 minutes of action. But an 11-0 run midway through the fourth quarter enabled the home team to pull away down the stretch.

Daniss Jenkins paced the offense with 26 points, eight dimes, and five boards. Jalen Duren posted a double-double of 22 points and 14 rebounds. He also had four assists.

Sixers vs Pistons NBA Pick

Here's a look at what you need to know for both teams ahead of this contest.

  • The Sixers are 7-3 (SU) in their last 10 games.
  • Philadelphia is 6-4 ATS in its previous 10 outings.
  • The Pistons are 8-2 (SU) in their last 10 contests.
  • Detroit is 7-3 ATS in its previous 10 matchups.

The Sixers have dropped four of the previous five meetings in this series. Detroit is a top-10 offensive team and a top-five defensive ball club. That, and a 35-14 record against the Eastern Conference this season, gives the Pistons the edge here.

Pick
Detroit Pistons
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