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Pistons vs Cavaliers NBA Pick: Divisonal Foes Face Off In Motown (Oct 27)

Published Oct 26, 10:29pm ET by

James Tillman - Betting Preview Analyst and Sports Writer

Last updated Oct 26, 10:29pm ET

Pick status
Pistons look to improve to 3-1 when they host the Cavaliers on Monday night.

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Updated Oct 26, 10:29pm ET

  • The Detroit Pistons improved to 2-1 following a 119-113 victory over the Boston Celtics.
  • Cleveland is also 2-1 after notching a 118-113 win against the Milwaukee Bucks.
  • These teams previously squared off on Mar. 28, with the Pistons claiming a 133-122 victory.

One of the games on Monday's NBA slate features the Detroit Pistons hosting the Cleveland Cavaliers. Who has the edge in our Pistons vs Cavaliers pick?

Detroit Pistons vs. Cleveland Cavaliers Overview Watch On: Peacock

DATE & TIME

MONDAY, OCTOBER 27, 2025 @ 7:00 PM ET
Detroit Pistons
Little Caesars Arena
Detroit, MI
Cleveland Cavaliers
GAME ODDS
BetOnline
Detroit Pistons +2.5 (-115)
Cleveland Cavaliers -2.5 (-105)

Pistons Seeking Third Consecutive Victory

Following a season-opening loss against the Bulls, Detroit has won two straight, including a 119-113 victory against the Boston Celtics on Sunday.

Detroit got off to a slow start, trailing 33-24 after the first quarter. But a 70-48 scoring edge in the the second and third quarters, propelled the home team to a six-point victory.

Cade Cunningham led the way with 25 ponts and eight assists on 2-for-5 shooting from 3-point range. Jalen Duren added 24 points, connecting on six of his 12 shot attempts and a 12-for-13 effort from the charity stripe.

Cleveland Also Aiming For Third Straight Victory

Like their opponent, the Cavaliers dropped their season-opener before responding with two straight victories. This includes a 118-113 win against the Milwaukee Bucks.

Cleveland led by as many as 18 points in the third quarter before the Bucks rallied to tie the game at 98 with 6:54 left to play. The Cavaliers responded with a 7-0 run, but the Bucks fought back, getting within 114-112 with 4.2 remaining in regulation.

Evan Mobley knocked down two free throws to help secure the five-point win for the Cavaliers. Donovan Mitchell was one of four starters who reached double figures. He finished with 24 points, four assists, and three rebounds. Mobley registered 23 points, eight rebounds, six assists, and three steals.

Injury / Suspension
PLAYER STATUS
Caris Levert INJURED
Jaden Ivy INJURED
Marcus Sasser INJURED
Darius Garland INJURED

Pistons vs Cavaliers NBA Pick

Here's a look at what you need to know for both teams ahead of this contest.

  • The Pistons are 5-15 straight-up (SU) in their last 20 games against Central Division opponents.
  • Detroit is 3-7 ATS in its previous 10 outings against Eastern Conference teams.
  • The Cavaliers are 12-1 in their last 13 contests against Detroit.
  • Cleveland is 0-5 against the spread in its previous five matchups.

Given the Cavaliers' dominance in this series, look for them to emerge victorious in this Central Division showdown.

Pick
Cleveland Cavaliers
New Player Bonus
50% up to $1000
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