Lakers vs Warriors NBA Pick: Divisional Foes Square Off In Los Angeles? (Oct 21)

Published Oct 19, 2:38pm ET by

James Tillman - Betting Preview Analyst and Sports Writer

Last updated Oct 19, 2:38pm ET

Pick status
The Lakers hope to upend their division rivals, when they host the Warriors on opening night.

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Updated Oct 19, 2:38pm ET

  • The Los Angeles Lakers finished the preseason with a 1-5 record.
  • Golden State fell to 3-2 in exhibition competition after a 106-103 loss to the LA Clippers.
  • The last regular-season meeting between these teams took place on Apr. 3, with the Warriors winning by a score of 123-116.

One of the games on Tuesday's NBA slate features the Los Angeles Lakers hosting the Golden State Warriors in the season opener for both ball clubs. Who has the edge in our Lakers vs Warriors pick?

Los Angeles Lakers vs. Golden State Warriors Overview Watch On: NBC

DATE & TIME

TUESDAY, OCTOBER 21, 2025 @ 10:00 PM ET
Los Angeles Lakers
Crypto.com Arena
Los Angeles, CA
Golden State Warriors
GAME ODDS
BetOnline
Los Angeles Lakers +1.5 (-105)
Golden State Warriors -1.5 (-115)

Lakers Conclude Preseason On A Sour Note Despite Solid Performance From Luka Doncic

Los Angeles faced a Sacramento squad that was missing multiple key players. The list included Keegan Murray, Domantas Sabonis, DeMar DeRozan, and Malik Monk.

Unfortunately, the Kings' lack of depth did not prevent them from rallying for a 117-116 victory, handing the Lakers their third straight loss and their fifth defeat in six preseason games.

Luka Doncic was spectacular, scoring a game-high 31 points, along with nine assists and five rebounds. The versatile guard also knocked down six of his 11 attempts from deep.

Golden State's Late-Game Rally Falls Short In Loss To Clippers

The Warriors fell behind by double digits after the first quarter and trailed by 11 points entering the fourth quarter. Golden State managed to get within three points down the stretch.

Ultimately, their rally came up short, as both Will Richard and L.J. Cryer missed game-tying 3-pointers in the final moments of this contest, enabling the Clippers to hold on for 106-103 victory.

Stephen Curry was the team's top scorer, finishing with 20 points, five rebounds, and four assists. He shot 7-for-16 overall and a respectable 4-for-8 from 3-point range.

Lakers vs Warriors NBA Pick

Following a 1-5 preseason record, Los Angeles enters this tilt as a 1.5-point underdog. Here's a look at what you need to know for both teams ahead of this contest.

  • The Lakers are 18-5 straight-up (SU) in their last 23 home games.
  • Los Angeles is 1-5 ATS in its previous six outings.
  • The Warriors are 9-4 in their last 13 road contests.
  • Golden State has covered the spread three times in its previous nine matchups.

Los Angeles has won three of the previous five meetings. At the same time, LeBron James isn't expected to return to the rotation until mid-November. With that in mind, the edge goes to the Golden State in this divisional showdown.

Pick
Golden State Warriors
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