Lakers vs Spurs NBA Pick: Who Extends Their Win Streak? (Dec 10)

Published Dec 9, 4:17pm ET by

James Tillman - Betting Preview Analyst and Sports Writer

Last updated Dec 9, 4:17pm ET

Pick status
In Wednesday's NBA action, the Lakers host the Spurs in a Western Conference showdown,

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  • The Lakers are 17-6 and tied for the second-best record in the Western Conference.
  • San Antonio improved to 16-7 following a three-point win against the Pelicans.
  • These teams previously squared off on Nov. 5, with the Lakers claiming a 118-116 victory.

One of the games on Wednesday's NBA slate features the Los Angeles Lakers hosting the San Antonio Spurs. Who has the edge in our Lakers vs Spurs pick?

Los Angeles Lakers vs. San Antonio Spurs Overview Watch On: Amazon Prime Video

DATE & TIME

WEDNESDAY, DECEMBER 10, 2025 @ 10:00PM ET
Los Angeles Lakers
Crypto.com Arena
Los Angeles, CA
San Antonio Spurs
GAME ODDS
BetOnline
Los Angeles Lakers -4.5 (-110)
San Antonio Spurs +4.5 (-110)

Lakers Coming Off Narrow Win Over Philadelphia

After suffering a 21-point loss against the Celtics, Los Angeles rebounded with a 112-108 victory over the Philadelphia 76ers.

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The Lakers trailed by seven points at halftime. But a 34-24 edge in the third quarter helped them overcome the deficit before holding on for a four-point win.

Luka Doncic put up a team-high 31 points, along with 15 rebounds and 11 assists. LeBron James added 29 points on 12-for-17 shooting from the field. He also tallied seven rebounds and six assists.

San Antonio Aiming For Its Fourth Victory In Five Games

The Spurs have won three of their previous four games, including a 135-132 victory against the New Orleans Pelicans on Monday night.

The Spurs held a 77-57 advantage at the break and appeared to be in control. However, New Orleans scored 45 points in the third quarter, flipping a 20-point deficit into a two-point lead heading into the fourth quarter.

Rookie Dylan Harper's floater and a pair of free throws from De'Aaron Fox gave San Antonio a three-point lead. The Pels had a chance to send the game into overtime, but Saddiq Bey's 3-point attempts was off the mark as the final buzzer sounded.

Harrison Barnes was one of seven players who reached double figures, finishing with 24 points. Harper led the second unit with 22 points and six assists in 26 minutes of action.

Lakers vs Spurs NBA Pick

Here's a look at what you need to know for both teams ahead of this contest.

  • The Lakers are 9-2 straight-up (SU) in their last 11 games.
  • Los Angeles is 13-6 ATS in its previous 19 outings.
  • The Spurs are 8-3 in their last 11 contests.
  • San Antonio is 1-4 ATS in its previous five matchups against the Lakers.

Los Angeles has won four of the last five meetings in this series, and is 5-1 in its previous six home outings against the Spurs. Based on the numbers, the edge goes to the purple and gold.

Pick
Los Angeles Lakers
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