Cavaliers vs Clippers NBA Pick: Who Has The Edge In This East vs West Matchup? (Nov 23)

Published Nov 22, 8:41pm ET by

James Tillman - Betting Preview Analyst and Sports Writer

Last updated Nov 22, 8:41pm ET

Pick status
The Cavaliers seek their fourth victory in five games when they host the Clippers on Sunday evening.

Shutterstock

Updated Nov 22, 8:41pm ET

  • The Cavaliers improved to 11-6 following a 120-109 victory against the Indiana Pacers.
  • Meanwhile, LA is 5-11 after defeating the Charlotte Hornets 131-116.
  • These teams previously squared off on Mar. 30, with the Cavaliers claiming a 127-122 victory.

One of the games on Sunday's NBA slate features the Cleveland Cavaliers hosting the LA Clippers. Who has the edge in our Cavaliers vs Clippers pick?

Cleveland Cavaliers vs. LA Clippers Overview Watch On: FDSOH

DATE & TIME

SUNDAY, NOVEMBER 23, 2025 @ 6:00PM ET
Cleveland Cavaliers
Rocket Arena
Cleveland, OH
LA Clippers
GAME ODDS
BetOnline
Cleveland Cavaliers -8.5 (-114)
LA Clippers +8.5 (-111)

Cavaliers Seek Fourth Win In Their Last Five Outings

After a 126-113 setback against the Raptors, Cleveland has won three of its last four games, including a 120-109 victory over the Indiana Pacers on Friday night.

ALSO SEE: Bears vs Steelers | Week 12 Odds and NFL Pick (Nov 23)

The Cavs held a 62-55 lead at the break, but thanks to a 21-9 burst during a critical four-minute stretch in the third quarter, Cleveland pulled away and stayed ahead for good.

Donovan Mitchell had an exceptional game, finishing with a team-high 34 points, along with nine rebounds and five assists. It marked the ninth time in 15 games this season in which the All-Star guard has scored at least 30 points.

James Harden Helps LA Snap Three-Game Skid

The Clippers have struggled this season, producing only five wins through their first 16 games. However, they recently ended a three-game skid with a 131-116 victory against the Charlotte Hornets on Saturday afternoon.

Although LA led by as many as 14 points in the first half, Charlotte pulled within 74-72 in the third quarter. But the Clippers broke the game open with a 22-10 run that enabled them to take a 14-point lead into the final frame.

James Harden was simply unstoppable. He scored a franchise-high of 55 points, including 27 in the opening frame. He also shot a respectable 10-for-16 from beyond the arc.

Cavaliers vs Clippers NBA Pick

Here's a look at what you need to know for both teams ahead of this contest.

  • The Cavaliers are 8-3 straight-up (SU) in their last 11 games.
  • Cleveland is 1-4 ATS in its previous five outings.
  • The Clippers are 2-9 in their last 11 contests.
  • LA is 12-6 ATS in its previous 18 matchups against the Cavaliers.

In addition to being the better team on paper, Cleveland is 7-3 in its last 10 November games, and boasts a 4-1 record in its previous five home outings against the Clippers. With that in mind, the edge goes to the Cavaliers.

Pick
Cleveland Cavaliers
New Player Bonus
50% up to $1000