Last updated Oct 30, 5:55am ET

The penultimate round of Premier League matches before the November international break is set for this weekend. All eyes will be on Anfield, as Liverpool bid to avoid suffering a sixth straight domestic defeat against Aston Villa. You can find our Premier League picks for matchday ten here.

Premier League Matchday 10 Schedule

StatInformation
WhenSaturday, November 1, 2025 – Monday, November 3, 2025
WhereVarious Stadiums, England
How to WatchNBC/USA

Premier League Matchday 10 Picks

Nottingham Forest vs. Man United

Ruben Amorim’s Man United appear to have turned a corner after recording three successive victories in the Premier League for the first time since February 2024.

Nottingham Forest come into this round of matches after losing their last four. A victory for United could see them move up to second in the standings, and given their recent reliable patch of form, it could be hard to bet against them when making Premier League picks.

Pick
Man United (+105)
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Burnley vs. Arsenal

Arsenal’s charge toward the Premier League title is showing no signs of slowing down. However, their inability to score from open play is irking fans. Labelled by many as a ‘set-piece team’, the Gunners have already netted eleven goals from set-piece scenarios.

Burnley’s confidence will be high ahead of this showdown after winning their last two. However, another win to nil could be the logical play for the Gunners on Saturday. 

Pick
Arsenal (-350)
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Fulham vs. Wolves

It has been a miserable start to the Premier League season for Wolves, as they are yet to win in their opening nine matches this season. Fulham have dropped to within three points of the drop zone after losing their last four.

Despite that, being back in front of their home fans could be a major boost for the Cottagers this weekend. They have avoided defeat in four of their last six meetings with Wolves at Craven Cottage. 

Pick
Fulham (-115)
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Brighton vs. Leeds

Brighton’s inconsistent form make them a tough team to predict. They come into this round after failing to win in three of their last five.

However, last weekend’s loss against Man United was their only defeat across that period. Leeds bounced back to form last weekend against West Ham. However, their away form could be a major issue this weekend. Therefore, Brighton look a good chance to record a seventh home win in eight against the Whites.

Pick
Brighton (-119)
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Crystal Palace vs. Brentford

Brentford have been in red-hot form in recent outings after winning each of their last three across all competitions.

Their counter-attacking style of play ensured that they landed a 3-2 win over Liverpool last weekend, while Crystal Palace’s confidence will be high after a 3-0 win over the same rivals in midweek. Brentford’s record in this fixture is fascinating, winning each of the last two, and losing just once in the last six. Therefore, a case could be made for the away win. 

Pick
Brentford (+299)
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Tottenham vs. Chelsea

Chelsea’s dominant historical record against Tottenham will be a notable angle this weekend. Spurs have struggled at home under Thomas Frank, winning just once in their four matches in 2025-26. Therefore, an away win could make plenty of appeal. Despite their inconsistent nature, Chelsea have won two of their four away matches, scoring an average of 2.75 goals per game.  +150

Liverpool vs. Aston Villa

Liverpool will be aiming to avoid suffering a sixth straight domestic defeat on Saturday when they take on Aston Villa. The team’s balance has been completely wrong throughout the campaign, and they were fortunate to lose 3-2 against Brentford last Saturday after being outplayed.

Aston Villa have won their last four games, and they have been defensively solid on the road after allowing just 0.75 goals per game. Huge stakes rest on this fixture, but a draw could be a likely outcome.

Pick
The Draw (+325)
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West Ham vs. Newcastle

West Ham’s miserable campaign sees them sit second bottom in the Premier League standings.

Their lack of pace across the field means that they rarely offer an offensive threat, which would be a major concern this weekend against one of the league’s best defenses. Newcastle have recorded wins in each of their last two matches across all competitions, and a third straight win could be achieved at the London Stadium.

Pick
Newcastle (-164)
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Man City vs. Bournemouth

Bournemouth have been one of the standout teams in the Premier League this season, and they sit second in the standings after avoiding defeat in their last eight matches.

Man City will be chasing a response following a shock defeat at Aston Villa last Saturday. Bournemouth’s counter-attacking prowess could ensure that they find the net this Sunday, and that may be enough to see them get an entertaining draw at the Etihad.

Pick
The Draw (+365)
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Sunderland vs. Everton

Sunderland’s win at Chelsea last Saturday means that they are riding high in fourth in the Premier League standings. Meanwhile, Everton’s attacking woes once again hindered their progress after a 3-0 loss against Tottenham last Sunday.

Everton’s attacking issues could see them dragged down the standings, while Sunderland’s experience and eye-catching attacking players could ensure that their dream start to the campaign continues on Monday.

Pick
Sunderland (+185)
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Alex Dudley
Alex Dudley

Sports Analyst and Betting Expert

Alex has over 15 years of experience in sports betting, specializing in soccer and horse racing. He uses his deep knowledge of markets and strategies to guide readers through disciplined and informed betting.

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