MLS: Philadelphia vs. New York City Picks — Tight Encounter Expected at Subaru Park? (Oct 4)

Two of the standout teams in the Eastern Conference in 2025 will lock horns at Subaru Park on Oct 4, 2025. You can find the odds and our Philadelphia vs. New York City picks here.

Philadelphia continue to be the team to catch in the East after winning 19 of their 32 matches in 2025. Confidence levels within the camp will be sky high after winning each of their last two matches to nil.

New York City have registered victories in two of their last three matches, and their confidence will be very high following a dramatic 3-2 success over city rivals, NY Red Bulls, last Sunday.

Philadelphia vs. New York City Overview

Odds

Philadelphia vs. New York City Head-to-Head Record

NYC recorded a 1-0 success in the reverse fixture between these sides in April. That victory was the perfect response after losing 5-1 against Philadelphia in September 2024.

Philadelphia Team News

Union were in dominant form last weekend after recording a 6-0 victory against D.C. United. Damiani, Vassilev, and Iloski all netted in the dominant win.

Possible Lineup

Blake (GK); Wagner, Glesnes, Makhanya, Harriel; Vassilev, Lukic, Jacques, Iloski; Uhre, Damiani

New York City Team News

Thiago Martins netted the dramatic winner in the New York derby last weekend. Julian Fernandez could be handed a start after impressing from the bench this Saturday.

Possible Lineup

Freese (GK); Gray, Martins, Haak, Gustavo; Fernandez, O’Neill, Perea, Wolf; Moralez, Fernandez

Philadelphia vs. New York City Picks

The odds indicate that the home win is the most likely outcome when making Philadelphia vs. New York City picks this weekend. However, a chance could be taken on NYC to upset the prices. The visitors have been in excellent recent form, and their strong offensive record could get them over the line in Philadelphia on Saturday.