Last updated Feb 6, 3:47am ET

Inter Miami were crowned MLS Cup champions for the first time in their history at the end of last season.

However, no team has successfully defended the title since LA Galaxy in 2012.

Despite that, just like the Seattle Seahawks being heavily favored for Super Bowl success, Lionel Messi’s team will be well-supported at the top of the betting to make history. You can find the latest MLS 2026 odds below, as well as our early picks for success.

MLS 2026 Schedule

The 2026 MLS season will get underway on Feb 21, with the regular season running until the start of November.

Interestingly, the 2026 season will be the final campaign under the spring-autumn format, with a summer-spring format introduced next season. Also, it is important to note that there will be a mid-season break between the end of May and mid-July due to the 2026 World Cup.

Once again this season, all matches will be broadcast exclusively on Apple TV.

MLS Cup 2026 Odds

TeamOdds
Inter Miami+400
Los Angeles FC+550
Vancouver Whitecaps+900
San Diego FC+1200
Seattle Sounders+1200
FC Cincinnati+1400
Philadelphia Union+1400
Other Selections+1600 & Bigger
New Player Bonus
50% up to $1000

ALSO SEE: Super Bowl LX: Patriots vs Seahawks Best Prop Bets, Odds and Picks (2026)

MLS Eastern Conference 2026 Odds

TeamOdds
Inter Miami+120
Philadelphia Union+700
FC Cincinnati+800
New York City FC+900
Columbus Crew+1000
Nashville SC+1400
Orlando City SC+1400
Other Selections+1800 & Bigger

MLS Western Conference 2026 Odds

TeamOdds
Los Angeles FC+275
Vancouver Whitecaps+400
San Diego FC+550
Los Angeles Galaxy+700
Seattle Sounders+800
Minnesota United+1400
Houston Dynamo+1600
Real Salt Lake+2000 & Bigger

Who Will Win The MLS Cup in 2026?

One of the most fascinating MLS seasons in history is set for 2026, with soccer set to come under the microscope ahead of the World Cup. Lionel Messi’s Inter Miami will be heavily favored to repeat their success, but the fact that no team since 2012 has gone back-to-back will be a concern.

The Vancouver Whitecaps enjoyed an excellent season to reach the MLS Cup final in 2025, and they are likely to strengthen during the off-season ahead of another challenge. Seattle Sounders also deserve huge respect after winning the Leagues Cup, which has proven to be a platform to bigger things.

How teams deal with the World Cup will be most interesting. However, the depth within the Los Angeles FC roster could be key. Heung Min Son joined mid-way through the season last term, and almost guided the team to Western Conference success despite limited time with teammates. In a full season, the South Korean could make his presence felt.

Pick
Los Angeles FC (+550)
New Player Bonus
50% up to $1000

Check back at a later date for a team-by-team guide ahead of MLS 2026 season.

Alex Dudley
Alex Dudley

Sports Analyst and Betting Expert

Alex has over 15 years of experience in sports betting, specializing in soccer and horse racing. He uses his deep knowledge of markets and strategies to guide readers through disciplined and informed betting.

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