Last updated Nov 3, 5:13am ET

The premier soccer competition in Europe returns this week, as matchday four in the Champions League is set for November 4-5. You can find some of our standout Champions League picks for the week ahead here.

Champions League Matchday 4 Schedule

StatInformation
WhenTuesday, November 4, 2025 – Wednesday, November 5, 2025
WhereVarious Stadiums, Europe
How to WatchCBS/Paramount+

Champions League Matchday 4 Picks

Juventus vs. Sporting Lisbon

A change in management had an immediate impact for Juventus in Serie A over the weekend, as the Old Lady recorded a 2-1 success against Cremonese. However, they will be aiming to get their Champions League campaign back on track against an in-form rival on Tuesday.

Sporting Lisbon have already won two of their three matches in the competition this season. However, that positive record could come to an end against a new-look Juventus under Luciano Spalletti, who will be much tougher defensively.

Pick
Juventus (-107)
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Liverpool vs. Real Madrid

Arne Slot’s Liverpool have been in poor form across all competitions so far this season. However, they were excellent winners in Frankfurt on MD3. Real Madrid are one of five teams that still have a perfect record in this season’s Champions League.

Los Blancos have won seven of their eleven clashes against the Reds, and their defensive solidity under Xabi Alonso could make them among the best value Champions League picks this week.

Pick
Real Madrid (+163)
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PSG vs. Bayern Munich

The current top two in the League Phase standings lock horns on matchday four in the Champions League. PSG have been impressive across their opening three matches, scoring a remarkable 13 goals.

Bayern Munich’s attacking prowess also sees them rank among the leading scorers in the competition at this early stage. This could be a potentially thrilling clash in Paris, but the hosts and their injury issues could ensure that the best value is for the away win when making Champions League picks.

Pick
Bayern Munich (+163)
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Ajax vs. Galatasaray

It has been an incredibly poor start to the Champions League for Ajax, and their struggles could be indicated against a talented Galatasaray on Wednesday.

The Turkish club have won each of their last two matches in the UCL, and their talented forward players could get a lot of joy against one of the weakest defenses in the competition in Amsterdam this week.

Pick
Galatasaray (+113)
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Benfica vs. Bayer Leverkusen

Benfica have been in impressive form since Jose Mourinho’s arrival, winning each of their last three without conceding.

Bayer Leverkusen’s form remains very inconsistent, and they were below their best when easily beaten by Bayern Munich on Saturday. The Portuguese club have typically excelled in home matches in the Champions League, and they could be the logical selection when making Champions League picks on Wednesday.

Pick
Benfica (+106)
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Man City vs. Borussia Dortmund

Pep Guardiola’s Man City are quietly going about their business in the Premier League this season, and their attacking prowess is catching the eye.

Borussia Dortmund have been one of the best attacking teams in the Champions League so far this term, but their defensive capabilities can be questioned. Due to that reason, a straightforward win for Man City is preferred when making Champions League picks.

Pick
Man City (-236)
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Alex Dudley
Alex Dudley

Sports Analyst and Betting Expert

Alex has over 15 years of experience in sports betting, specializing in soccer and horse racing. He uses his deep knowledge of markets and strategies to guide readers through disciplined and informed betting.

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