Angels vs Cubs MLB Odds, Picks, and Predictions (April 1)

Published Apr 1, 7:32am ET by

Demilade Adelekun - Betting Preview Analyst and Sports Writer

Last updated Apr 1, 7:32am ET

Pick status

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Updated Apr 1, 7:32am ET

  • Yusei Kikuchi returns to the hill after allowing eight hits in a shaky 4.1-inning debut against Houston.
  • Matthew Boyd looks to erase the memory of his Opening Day disaster, where he surrendered six runs in just 3.2 frames against Washington.
  • The series finale pits two 3-loss teams desperate to climb above .500 before hitting the road.
Chicago Cubs vs. Los Angeles Angels Overview Watch On: MLB TV

DATE & TIME

Wednesday, April 1, 2026 @ 2:20 PM ET
Chicago Cubs
Wrigley Field
Chicago, IL
Los Angeles Angels
GAME ODDS
BetOnline
Chicago Cubs -171
Los Angeles Angels +141

Kikuchi Seeks Consistency After Mixed Angels Debut

Yusei Kikuchi enters his second start of 2026, trying to build on the success of his first Angels season. The southpaw went 7-11 with a 3.99 ERA, 1.42 WHIP, and 1.8 bWAR across 178.1 innings in 2025, earning his second All-Star selection.

Kikuchi tied for the American League lead with 33 starts and posted 174 strikeouts, but his 1.42 WHIP revealed the traffic issues that plagued him all season. He allowed eight hits over 4.1 innings against Houston in his 2026 debut, showing the same command struggles that limited his effectiveness last year.

Mike Trout is scorching hot at with two homers and three RBIS through five games, looking every bit like the three-time MVP of old.

Jorge Soler has been a true slugger for the team. Batting only at a .174 average, but is currently in the top 15 in the league in RBIs at 5.

Boyd Looks to Rebound from Opening Day Nightmare

Matthew Boyd's stellar 2025 campaign earned him Opening Day honors, but the lefty's season debut was a disaster. After going 14-8 with a 3.21 ERA, 1.09 WHIP, and 2.5 bWAR in 179.2 innings, Boyd was shelled for six runs on six hits and a walk in just 3.2 innings against Washington.

The 35-year-old All-Star showed signs of fatigue down the stretch last year, posting a 5.31 ERA in September after carrying the rotation through the summer. His 154 strikeouts demonstrated solid stuff, but the abbreviated Opening Day outing raised questions about whether last year's workload took a toll.

On the other side of the mound, the Cubs lineup presents a stiff test for Kikuchi's slider-heavy approach. Alex Bregman has already launched two home runs in his Cubs debut series and thrives against lefties who leave pitches over the plate. Kikuchi's flyball tendencies and Wrigley's wind could spell trouble if the Cubs get him elevated.

Angel vs Cubs Pick

Boyd's Opening Day collapse creates value for the Angels. The Cubs' lefty allowed six runs and couldn't escape the fourth inning against Washington. Boyd has shown susceptibility to power lineup, and the Angels have a lot of slugging power on their team. Our pick is the Angels +141.

Pick
Angels +141
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